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A range of therapeutic targets are likely to be relevant for reducing risk of suicide in TRD. Here's what you need to know.

Objective: The Interpersonal Theory of Suicide (ITS) could help identify differences in groups of suicidal adolescents and inform treatment. Method: Latent Profile Analysis (LPA) using thwarted belongingness (TB), perceived burdensomeness (PB), hopelessness, and capability was conducted on data from an at-risk clinical sample (N = 500). The ITS prediction that changes in TB and PB are associated with changes in suicidal ideation was tested using admission and discharge data. Results: Latent Profile Analysis identified three profiles with increasing complexity and severity on ITS factors. The p...

By: Amy Walden | Published: February 21, 2024 | 9:21 am | SHARE: According to the Gun Violence Archive, the United States reported 656 mass shootings in 2023. W

Suicide is the primary cause of death among adolescents in Australia, and it continues to be a significant cause of mortality globally, with rates on the rise. The Interpersonal Theory of Suicide (ITS) posits that thwarted belongingness (low-belongingness) and perceived burdensomeness (burdensomeness) lead to suicide desire, and hopelessness moderates the intensity of the wish to die. Acquired capability (capability) is theorised to moderate the relationship between these factors and suicide desire, and is positively associated with resoluteness to enact a lethal suicide attempt. While the ITS...

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