Discovery offers potential for stripping tumors of T cell protection
Date Time Discovery offers potential for stripping tumors of T cell protection First author Seon Ah Lim, Ph.D., and corresponding author Hongbo Chi, Ph.D., both of St. Jude Immunology, contributed to research that raises the potential for treatments that render tumors more vulnerable to cancer immunotherapy. Immunologists at St. Jude Children’s Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and ...