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You get disoriented. it can be uncomfortable. it can lead to panic attacks or anxiety attacks in people. >> how do you know when you've done too much? >> simple tasks become very frustrating, like mixing paint, and then just sort of get into this state of, you know -- >> and why that happens is exactly what columbia university neuroscientist carl hart is investigating. >> exhale. >> research subjects in his lab smoke marijuana and then take a variety of cognitive tests. >> the effects will be disruption in memory, disruptions in inhibitory control. they will become slower at cognitive function...

It can be uncomfortable. it can lead to panic attacks or anxiety attacks in people. >> how do you know when you've done too much? >> simple tasks become very frustrating, like mixing paint, and then just sort of get into this state of, you know -- >> and why that happens is exactly what columbia university neuroscientist carl hart is investigating. >> exhale. >> research subjects in his lab smoke marijuana and then take a variety of cognitive tests. >> the effects will be disruption in memory, disruptions in inhibitory control. they will become slower at cognitive functioning, a wide range of ...

>> how do you know when you've done too much? >> simple tasks become very frustrating, like mixing paint, and then just sort of get into this state of, you know -- >> and why that happens is exactly what columbia university neuroscientist carl hart is investigating. >> exhale. >> research subjects in his lab smoke marijuana and then take a variety of cognitive tests. >> the effects will be disruption in memory, disruptions in inhibitory control. they will become slower at cognitive functioning, a wide range of things. these effects are temporary, but they're pretty pronounced, and they are cle...

This and that and just sort of looking and being as present as possible. >> amir does caution that it's a delicate balance for him. >> it would make me apprehensive, maybe a little paranoid. just too analytical. >> you can get paranoid and have disorganized thinking. you get disoriented. it can be uncomfortable. it can lead to panic attacks or anxiety attacks in people. >> how do you know when you've done too much? >> simple tasks become very frustrating, like mixing paint, and then just sort of get into this state of, you know -- >> and why that happens is exactly what columbia university neu...

>> simple tasks become very frustrating, like mixing paint, and then just sort of get into this state of, you know -- >> and why that happens is exactly what columbia university neuroscientist carl hart is investigating. >> exhale. >> research subjects in his lab smoke marijuana and then take a variety of cognitive tests. >> the effects will be disruption in memory, disruptions in inhibitory control. they will become slower at cognitive functioning, a wide range of things. these effects are temporary, but they're pretty pronounced, and they are clear. >> and it's slowly becoming clear to scien...