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Protein purification at low temperatures is crucial for preserving protein integrity and preventing proteolytic degradation, as well as managing protein aggregation tendencies. This application note offers general principles for successful protein purification in cold environments, with ÄKTA™ systems, chromatography resins, and prepacked columns typically performing well at 4°C to 8°C, similar to room temperature results. ....

Application Note , Application Notes , Scientific Posters , Case Studies , Application Articles , Laboratory Methods , Food And Beverage , Clinical Diagnostics , Life Science , Drug Discovery ,

Integrity and purity of mRNAs from lipid nanoparticles

To ensure the quality of LNP-based drugs, comprehensive characterization of these sophisticated molecules is paramount. Explore how to achieve high-quality, robust assessment of the integrity and size of mRNA molecules encapsulated in LNPs. ....

Application Note , Application Notes , Scientific Posters , Case Studies , Application Articles , Laboratory Methods , Food And Beverage , Clinical Diagnostics , Life Science , Drug Discovery ,