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First-line therapy with axicabtagene ciloleucel induced objective responses in 89% of patients with high-risk large B-cell lymphoma, according to phase 2 study results.An estimated 91% of patients treated with a single infusion of the chimeric antigen receptor T-cell therapy remained alive at 12 months, a primary analysis of the ZUMA-12 trial showed.
Age variability in symptom onset of Alzheimer’s disease in those with Down syndrome was comparable to those who experienced autosomal dominant AD, while mortality was also similar, according to a study published in JAMA Network Open. “Down syndrome is a complex condition with multiple associated comorbidities that vary throughout the lifespan. Improvements in health care ... have
For some atopic dermatitis patients treated with tralokinumab who do not reach clear or almost clear skin, clinically meaningful results can still occur. “The FDA approves drugs in atopic dermatitis based solely on the proportion of patients or percentage of patients who get clear or almost clear after 16 weeks of treatment,” Eric Simpson, MD, director of the clinical studies unit at
Adults with diabetes and neuropathy experience significantly more fatigue than those with diabetes and no neuropathy and people without diabetes, according to a speaker at the American Association of Clinical Endocrinology annual meeting.
Interdisciplinary care was associated with higher odds of being listed for kidney transplant among patients with incident end-stage kidney disease in underrepresented groups, according to this study.Further, researchers found interdisciplinary care provides better ESKD preparedness than the usual nephrology care in this population.