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Genomic sequencing of tumors enabled 107 patients with pediatric cancer who experienced relapse to receive an appropriate matched therapy that is not standard of care, according to study results reported in Cancer Discovery. The international MAPPYACTS precision medicine clinical trial sought to use results of genetic profiling of tumors to suggest treatments targeted to molecular alterations.
According to published results, surgeons should make the cost-conscious decision to treat displaced midshaft clavicle fractures with a sling compared with open reduction and internal fixation with a plate.To determine the cost-effectiveness of open reduction and internal fixation (ORIF) with a plate vs. sling for displaced midshaft clavicle fractures, Kevin C. Wall, MD, MPH, and colleagues
Infectious Disease News | The COVID-19 pandemic has had a significant impact on medicine in the past 2-plus years. We asked Nancy S. Reau, MD, Richard B. Capps Chair of Hepatology and professor in the department of internal medicine, division of digestive diseases and nutrition at Rush University, if it has changed the perception of the hepatitis C virus care cascade.
ANI Pharmaceuticals Inc. has received FDA approval of its abbreviated new drug application for clorazepate dipotassium tablets, according to a company press release.ANI stated that this is a generic version of Tranxene (clorazepate dipotassium, Sanofi), which is indicated for managing anxiety disorders, according to the FDA package insert.
Infectious Disease News | The mosquito is one of the world’s most impactful forces. The breadth of transmissible diseases caused by a mosquito bite, including malaria, has helped shape human history.Malaria is caused by infection of erythrocytes with protozoan parasites of the genus Plasmodium that are transmitted through the bites of infected female Anopheles mosquitoes. In 2020, there were an estimated 241 million