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Apellis Pharmaceuticals submitted a new drug application to the FDA for intravitreal pegcetacoplan, a targeted C3 therapy for the treatment of geographic atrophy secondary to age-related macular degeneration, according to a press release.The submission is based on the results of the phase 3 DERBY and OAKS studies, as well as the phase 2 FILLY study. Pegcetacoplan demonstrated reduction in
Stem cell therapy still has many hurdles to clear before becoming a viable therapeutic option for age-related macular degeneration, but it may have the potential to transform treatment in the future.“Overall, we have a huge problem with a major unmet need,” Rajesh C. Rao, MD, Leonard G. Miller Professor of Ophthalmology and Visual Sciences and associate professor in the departments of
Elevating the rheumatology’s profile to policymakers, medical students and patients through advocacy and education is critical for the specialty’s future, according to EULAR President Annamaria Iagnocco, MD.“EULAR is 75 years old but looks much younger,” Iagnocco said in her opening remarks of the EULAR 2022 Congress. “The past is what we know and serves as a
The presence of chronic obstructive pulmonary disease is not associated with intra-hospital or 1-year outcomes for patients with mitral regurgitation undergoing transcatheter mitral valve repair, data from a single-center study show.“Due to the concomitant risk factors, a relevant percentage of patients with CVD needing cardiac surgery or intervention have chronic obstructive pulmonary
SAN DIEGO — Vedolizumab and ustekinumab associated with a lower risk for infection-related hospitalizations compared with anti-tumor necrosis factor agents in patients who initiated inflammatory bowel disease therapy at an older age. “It used to be thought that IBD becomes a milder disease with age and, therefore, there never was a tremendous investment in better understanding modern