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Why is it so difficult to find a treatment for Huntington's Disease?

The Huntington’s disease (HD) community has recently experienced setbacks, but a new research report may reignite hope, from an unexpected source: the

Spain , Madrid , Severo-ochoa , Jane-mervar , Jonathan-monkemeyer , Khan-academy , Science-translational-medicine , Young-investigators-review , Centro-de-biolog , Molecular-severo-ochoa ,

First Confirmed Case Of Bird flu Recorded In Mainland Antarctica, Experts Concern On The Welfare Of The Birds In The Region

Experts confirmed the first case of bird flu on the mainland of Antarctica. Read more here. Officials have confirmed that bird flu has spread to mainland Antarctica for the first time.

Antarctica , United-kingdom , United-states , Madrid , Spain , Argentina , Centro , Araucaníci , Chile , South-africa , America , Argentine

Scientists confirm first cases of bird flu on mainland Antarctica

Fears for penguin colonies after the discovery of the highly contagious H5N1 virus in two dead skuas

Antarctica , Spain , United-kingdom , United-states , Centro , Araucaníci , Chile , Argentina , South-africa , Madrid , British , Spanish

Why it's so difficult to find a treatment for Huntington's Disease?

The Huntington’s disease (HD) community has recently experienced setbacks, but a new research report may reignite hope, from an unexpected source: the

Spain , Madrid , Severo-ochoa , Jane-mervar , Jonathan-monkemeyer , Khan-academy , Science-translational-medicine , Young-investigators-review , Centro-de-biolog , Molecular-severo-ochoa ,

Scientists create mouse avatars to treat mult

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra (Spain), has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases. These artificial mice can mimic the genetic and immunological diversity of the origin and evolution of this disease in patients. This advance will allow researchers to design more effective and personalized therapies for multiple myeloma. Nature Medicine publishes this study that opens a pathway for research into other non-curable hematological and solid tumors.

Tsukuba , Ibaraki , Japan , United-states , Switzerland , Spain , Lasarte , Pais-vasco , Spanish , Marta-larrayoz , Amaia-etxebeste , Cima-hemato

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

United-states , Japan , Switzerland , Spain , Tsukuba , Ibaraki , Spanish , Navarra-idi , Emily-henderson , Marta-larrayoz , Severo-ochoa , Cima-hemato

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice

Coronaviruses (CoVs) have the largest genome among RNA viruses and a proofreading exoribonuclease (nsp14) responsible for high-fidelity RNA synthesis. These properties make CoVs very attractive for the establishment of vaccine platforms or viral vectors since they can stably store large amounts of information without genome integration. Using Middle East respiratory syndrome coronavirus (MERS-CoV) as a model, a propagation-deficient RNA replicon was generated by removing the envelope (E) gene (essential for viral morphogenesis and involved in virulence) and accessory genes 3, 4a, 4b, and 5 (responsible for antagonism of the innate immune response): MERS-CoV-Δ[3,4a,4b,5,E]. This replicon is strongly attenuated and elicits sterilizing protection after a single immunization, making it a promising vaccine candidate and an interesting platform for vector-based vaccine development.

Germany , Jouy-en-josas , France-general- , France , Netherlands , Madrid , Spain , Heidelberg , Baden-wüberg , Berkhout , Noord-holland , Venezuela

Does a Vitamin Deficiency in the Brain Lie Behind Huntington's Disease?

Does a Vitamin Deficiency in the Brain Lie Behind Huntington's Disease?
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Spain , Madrid , Jonathan-monkemeyer , Severo-ochoa , Jane-mervar , Science-translational-medicine , Centro-de-biolog , Molecular-severo-ochoa ,

Boosting Chemotherapy by Blocking Protein in DNA Repair

Boosting Chemotherapy by Blocking Protein in DNA Repair
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Spain , Spanish , Luis-blanco , Severo-ochoa , Replication-group , Spanish-national-cancer-research-center , Centro-de-biolog , Molecular-severo-ochoa , ஸ்பெயின் , ஸ்பானிஷ் , லூயிஸ்-ப்ளான்க்கோ , சேவேரோ-ஆசோவ

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Repressing a protein that facilitates DNA repair to potentiate chemotherapy
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United-states , Luis-blanco , Severo-ochoa , Emily-henderson , Replication-group , Experimental-therapeutics-programme , Washington-university-st-louis , Centro-de-biolog , Molecular-severo-ochoa , Washington-university , Therapeutics-programme , ஒன்றுபட்டது-மாநிலங்களில்