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Women with cystic fibrosis have higher rates of pulmonary exacerbations compared with men, with differences appearing early in life, researchers reported at the virtual North American Cystic Fibrosis Conference.Researchers conducted a retrospective cohort study utilizing data from the Cystic Fibrosis Foundation Patient Registry from 2006 to 2019. Among 40,782 individuals with cystic fibrosis, the
Increased use of neoadjuvant chemotherapy appeared associated with improvements in short-term mortality without sacrificing long-term survival in ovarian cancer, according to a comparative effectiveness research study in JAMA Oncology.The difference-in-differences analysis compared cancer programs with high use vs. low use of neoadjuvant chemotherapy (NACT), as researchers understood the
Patients with glaucoma who did not achieve clinician-defined target IOP had more rapid visual field worsening, according to data published in Ophthalmology. While other studies have explored the effects of achieving prespecified target IOP, few have studied the clinician-set target.
Although more than 25% of contemporary FDA-approved cancer therapies required cardiovascular warnings, post-marketing issuance of the warnings trailed clinical approval by several years, according to a research letter in JAMA Oncology.“Our findings suggest the need for increased vigilance to potentially limit cardiotoxic events, such as arrhythmias. This is especially important as many
Untreated perinatal anxiety disorders and related stress or depression among mothers pose risks to offspring, according to a presenter at Psych Congress. Kimberly Brandt, DO, PMH-C, a perinatal psychiatrist at the University of Missouri School of Medicine, said the benefits of treating these disorders outweigh potential risks.