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Biological Therapy Could be Another Option to Antibiotics by Angela Mohan on  February 23, 2021 at 12:07 PM Human monoclonal antibodies can act as a substitute for the traditional chemical antibiotics and protect from pathogenic bacterial challenge, as per the study led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty. The research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The antibodies were isolated from a patient who had succumbed to active tuberculosi...

Study Traces Back the Evolutionary History of Antibiotic Resistance by Colleen Fleiss on  January 9, 2021 at 3:06 AM Gothenburg scientists have traced back the evolutionary history of antibiotic resistance genes. In almost all cases where an origin could be determined, the gene started to spread from bacteria that, themselves, can cause disease. While human DNA is only passed down from parent to child, bacteria also have the habit of sharing some of their genes across species. This often applies to genes that make the bacteria resistant to antibiotics. ‘The use and ove...

New Group of Antibiotics Active Against Various Bacteria by Angela Mohan on  December 24, 2020 at 11:00 AM Nature, by Wistar Institute scientists. "We took a creative, double-pronged strategy to develop new molecules that can kill difficult-to-treat infections while enhancing the natural host immune response," said Farokh Dotiwala, M.B.B.S., Ph.D., assistant professor in the Vaccine & Immunotherapy Center and lead author of the effort to identify a new generation of antimicrobials named dual-acting immuno-antibiotics (DAIAs). Current antibiotics target nucleic acid and prot...