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Testosterone Therapy Economical for Men With Low Testosterone

Cost utility analysis of data from placebo-controlled trials suggests cost-effectiveness in most scenarios for men younger than 75 years.

United-kingdom , Rodolfo-hern , Health-economics-research-unit , University-of-aberdeen , Beck-depression-inventory ,

Slamdance Interview: A Ballot Box Revolution in Petro

U.S. filmmakers hit the campaign trail with the Colombian president

Bucaramanga , Santander , Colombia , Colombian , Trevor-martin , Rodolfo-hern , Tom-laffay , Federico-fico-guti , Gustavo-petro , Sean-mattison , Julian-roberts , Augusto-rodr

Slamdance examines the first progressive left president of Colombia

Emmy Award-winning filmmaker Sean Mattison's

Colombia , Barranquilla , Atláico , Colombian , Federico-guti , Gustavo-petro , Sean-mattison-petro , Sean-mattison , Trevor-martin , Rodolfo-hern , Hilton-hotel-park-city , Slamdance-film

The Venezuelan Exodus: A New Migrant Diaspora in the United States

Over the last year an unprecedented wave of Venezuelan immigrants flooded the US-Mexico border
prompting talk of a new migrant crisis. The Venezuelan migration to the US is part of the largest such
exodus in the history of the Americas. The scale and scope of the Venezuelan migration crisis raises
important questions. Why have so many Venezuelans opted to leave their country in recent years? How
have Venezuelan migrants fared in other countries and how in turn have they affected those countries
that receive them? What dangers and opposition do they face on their journeys? What is the future of
Venezuelan migrants in the US? And how is this phenomenon impacting US-Venezuelan relations? In
this article, we draw on dozens of semi-structured interviews and informal conversations conducted
between 2019 and the present by the authors with Venezuelan migrants in Colombia, Mexico, and the
United States. Combining these primary sources with other available academic and media-based
publications, we explore why so many Venezuelans have left their country in recent years, the realities
awaiting them in receiving countries and along their journeys, and what ultimately this means for this
new diaspora in the United States and for the country itself.

Venezuela , United-states , Colombia , Chile-to , Cajamarca , Peru , Lima , Cuba , China , Caribbean-sea , Belize-general- , Belize

The Venezuelan Exodus: A New Migrant Diaspora in the United States

Over the last year an unprecedented wave of Venezuelan immigrants flooded the US-Mexico border
prompting talk of a new migrant crisis. The Venezuelan migration to the US is part of the largest such
exodus in the history of the Americas. The scale and scope of the Venezuelan migration crisis raises
important questions. Why have so many Venezuelans opted to leave their country in recent years? How
have Venezuelan migrants fared in other countries and how in turn have they affected those countries
that receive them? What dangers and opposition do they face on their journeys? What is the future of
Venezuelan migrants in the US? And how is this phenomenon impacting US-Venezuelan relations? In
this article, we draw on dozens of semi-structured interviews and informal conversations conducted
between 2019 and the present by the authors with Venezuelan migrants in Colombia, Mexico, and the
United States. Combining these primary sources with other available academic and media-based
publications, we explore why so many Venezuelans have left their country in recent years, the realities
awaiting them in receiving countries and along their journeys, and what ultimately this means for this
new diaspora in the United States and for the country itself.

Venezuela , Mexico , China , Guyana , Colombia , Tijuana , Baja-california , Florida-international-university , Florida , United-states , California , Maracaibo

In Colombia, public sentiment shifts right as the left loses steam

A year and a half into the government of Gustavo Petro, the president is losing support among centrists, according to a new survey by Cifras y Conceptos

United-states , Argentina , Colombia , Colombians , American , Colombian , Jorge-restrepo , Carlos-fernando-gal , Cifrasy-conceptos , Yolanda-ruiz , Rodolfo-hern , Javier-milei

Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled…

Objective To assess the clinical and cost effectiveness of conservative management compared with laparoscopic cholecystectomy for the prevention of symptoms and complications in adults with uncomplicated symptomatic gallstone disease.

Design Parallel group, pragmatic randomised, superiority trial.

Setting 20 secondary care centres in the UK.

Participants 434 adults (>18 years) with uncomplicated symptomatic gallstone disease referred to secondary care, assessed for eligibility between August 2016 and November 2019, and randomly assigned (1:1) to receive conservative management or laparoscopic cholecystectomy.

Interventions Conservative management or surgical removal of the gallbladder.

Main outcome measures The primary patient outcome was quality of life, measured by area under the curve, over 18 months using the short form 36 (SF-36) bodily pain domain, with higher scores (range 0-100) indicating better quality of life. Other outcomes included costs to the NHS, quality adjusted life years (QALYs), and incremental cost effectiveness ratio.

Results Of 2667 patients assessed for eligibility, 434 were randomised: 217 to the conservative management group and 217 to the laparoscopic cholecystectomy group. By 18 months, 54 (25%) participants in the conservative management arm and 146 (67%) in the cholecystectomy arm had received surgery. The mean SF-36 norm based bodily pain score was 49.4 (standard deviation 11.7) in the conservative management arm and 50.4 (11.6) in the cholecystectomy arm. The SF-36 bodily pain area under the curve up to 18 months did not differ (mean difference 0.0, 95% confidence interval −1.7 to 1.7; P=1.00). Conservative management was less costly (mean difference −£1033, (−$1334; −€1205), 95% credible interval −£1413 to −£632) and QALYs did not differ (mean difference −0.019, 95% credible interval −0.06 to 0.02).

Conclusions In the short term (≤18 months), laparoscopic surgery is no more effective than conservative management for adults with uncomplicated symptomatic gallstone disease, and as such conservative management should be considered as an alternative to surgery. From an NHS perspective, conservative management may be cost effective for uncomplicated symptomatic gallstone disease. As costs, complications, and benefits will continue to be incurred in both groups beyond 18 months, future research should focus on longer term follow-up to establish effectiveness and lifetime cost effectiveness and to identify the cohort of patients who should be routinely offered surgery.

Trial registration ISRCTN registry [ISRCTN55215960][1].

The datasets generated during the study will be available upon reasonable request from the corresponding author.

[1]: /external-ref?link_type=ISRCTN&access_num=ISRCTN55215960

Italy , Netherlands , Norway , Glasgow , Glasgow-city , United-kingdom , Newport , United-states , London , City-of , Bristol , America

"We are concerned about the rise of populism based on messianic leading figures"

Antonio Garrastazu is the director of the International Republican Institute. In dialogue with LPO, he talks about the growing US concern about authoritarian leaders who come to power through voting.

Bolivia , Honduras , China , Dominican-republic , Colombia , Paraguay , Nicaragua , Belize , Ukraine , United-states , Haiti , Guatemala

Finance Colombia » Daniel Quintero Abruptly Resigns as Mayor of Medellín

Finance Colombia » Daniel Quintero Abruptly Resigns as Mayor of Medellín
financecolombia.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from financecolombia.com Daily Mail and Mail on Sunday newspapers.

Arauca , Colombia , Antioquia , Cundinamarca , Cartagena , Bolír , Sincelejo , Sucre , Bucaramanga , Santander , Colombian , Federico-guti

Finance Colombia » With Tulio Gómez Possibly Out of the Race, Dilian Francisca Toro Looks Poised to Once Again Become Governor of Valle del Cauca

Finance Colombia » With Tulio Gómez Possibly Out of the Race, Dilian Francisca Toro Looks Poised to Once Again Become Governor of Valle del Cauca
financecolombia.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from financecolombia.com Daily Mail and Mail on Sunday newspapers.

La-silla , Departamento-de-norte-santander , Colombia , Pradera , Tolima , Palmira , Valle-del-cauca , Centro , Araucaníci , Chile , Santiago , Regióetropolitana