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Frontiers | Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model


1
1Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, United States
2Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, United States
3Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, United States
4Department of Pathology, Division of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL, United States
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional
in vitro studies fail to replicate the complexity of these interactions. Herein, we developed three-dimensional (3D) lung tumor models that mimic the human TME and demonstrate tumor-stromal crosstalk mediated by extracellular vesicles (EVs). EVs released by tumor cells, independent of p53 status, and fibroblasts w ....

New York , United States , Franklin Lakes , Fort Collins , San Diego , South Korea , La Jolla , Malvern Panalytical , Olaf Kutsch , Georgem Jr , Victor Thannickal , Ebrahimi Warkianim Upregulation , Biochim Biophys Acta , Santa Clara , Razavi Bazaz , Agilent Technologies , Pathology Core Research Lab , Living Image Software Perkin Elmer , A Powerful Tool In Tumor Research , National Cancer Institute Center Support Grant , Imaging Software , Modified Eagle , Atlas Biologicals , American Type Culture Collection , Supplemental Figure , Detection Kit ,

Project MUSE - The Holocaust and American Public Memory, 1945-1960


Holocaust and Genocide Studies 17.1 (2003) 62-88
The Holocaust and American Public Memory, 1945-1960
San Diego State University
Abstract: Until the 1960s, many scholars assert, most Americans
awareness of the Holocaust was based upon vague, trivial, or inaccurate
representations. Yet the extermination of the Jews was remembered in
significant ways, this article posits, through World War II accounts,
the Nuremberg trials, philosophical works, comparisons with Soviet
totalitarianism, Christian and Jewish theological reflections, pioneering
scholarly publications, and mass-media portrayals. These early postwar
attempts to comprehend the Jewish tragedy within prevailing cultural
paradigms provided the foundation for subsequent understandings of
that event.
 
Between the end of the war and the 1960s, as anyone who has lived ....

United States , University Of Chicago , United Kingdom , Riverside Park , New York , San Diego , Garden City , Union Theological Seminary , University Of Washington , German Church , Columbia University , Northwestern University , Harvard University , Holocaust Museum , Syracuse University , West Germany , New Yorker , Great Britain , State Of Israel , Telford Taylor , Milton Steinberg , Max Horkheimer , Stephenj Whitfield , Martin Jay , Franklin Littell , Nostra Aetate ,