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Vaccines delivered via skin may offer better protection against respiratory diseases Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century. Until very recently, smallpox vaccine was delivered using a technique known as skin scarification (s.s.), in which the skin is repeatedly scratched with a needle before a solution of the vaccine is applied. Almost all other vaccines today are delivered via intramuscular injection, with a needle going directly into the muscle...

Vaccine Delivery through Skin Scarification Could Be Solution in Controlling Respiratory Diseases January 28, 2021 Many countries are now becoming keenly aware that the creation of a vaccine to help control the spread of virulent respiratory infections like COVID-19 is only half the battle. Easy and effective vaccine delivery methods are a critically important step in the process. Yet, we need look no further than the 20 th century for effective methods to help deliver pandemic vaccines. Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success stor...

Skin scarification could be effective in vaccinating people against respiratory illnesses: Study January 28, 2021 × The technique was found to be effective in generating T cells that home to the lungs Skin scarification may help generate lung T cells and provide protection against infectious diseases, including Covid-19, sccording to study published in the journal NPJ Vaccines. "We have known for years that this technique was a good way to generate T cells that would home to the skin, but our study shows that skin scarification is also an effective way to generate T cells that home to the ...

 E-Mail Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century. Until very recently, smallpox vaccine was delivered using a technique known as skin scarification (s.s.), in which the skin is repeatedly scratched with a needle before a solution of the vaccine is applied. Almost all other vaccines today are delivered via intramuscular injection, with a needle going directly into the muscle, or through subcutaneous injection to the layer of tissue beneath the skin....