It may improve overall function and cognition. and may slow the worsening of symptoms for a while. vo: namenda xr doesn't change how the disease progresses. it shouldn't be taken by anyone allergic to memantine, or who's had a bad reaction to namenda xr or its ingredients. before starting treatment, tell their doctor if they have, or ever had, a seizure disorder, difficulty passing urine, liver, kidney or bladder problems, and about medications they're taking. certain medications, changes in diet, or medical conditions may affect the amount of namenda xr in the body and may increase side effec...