"The role of dietary intake of flavonoids and anthocyanins on vascular " by Vinicius Andre do Rosario
Vascular health plays a major role in several human disorders, particularly in cardiovascular diseases (CVD) (1,2). The endothelium can be considered an organ that regulates vascular homeostasis by maintaining an appropriate vascular tone, platelet activity, leukocyte adhesion and angiogenesis. When one or more of these components is compromised due to impaired endothelial vascular signalling, endothelial dysfunction (ED) may occur (1). One of the main key metabolic manifestations of ED is reduced nitric oxide (NO) bioavailability. NO is an important signalling molecule that regulates various ...