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Frontiers | Excretion of Heavy Metals and Glyphosate in Urine and Hair Before and After Long-Term Fasting in Humans

Background: Dietary exposure to environmental pollutants in humans is an important public health concern. While long-term fasting interrupts the dietary exposure to these substances, fat mobilization as an energy source may also release bioaccumulated substances. This was, to our knowledge, only investigated in obese people decades ago. This study explored the effects of 10-days fasting on the excretion of heavy metals and glyphosate. Methods: Urinary levels of arsenic, chromium, cobalt, lead, nickel, mercury and glyphosate were measured before and after 10 fasting days in 109 healthy subjects. Additionally, hair analysis was done before and ten weeks after fasting in 22 subjects. Results: Fasting caused a decrease in body weight, and in urinary arsenic (by 72 %) and nickel (by 15 %) concentrations. A decrease in lead hair concentrations (by 30 %) was documented. Urinary mercury levels were unchanged for chromium, cobalt and glyphosate, which were undetectable in most of the subjects. Additionally, fatigue, sleep disorders, headache and hunger were reduced. Body discomfort symptoms diminished four weeks after food reintroduction. Conclusions: The results of this study provide the first insights into the changes in heavy metal excretion caused by long-term fasting. Further studies focusing on the kinetics of efflux between different compartments of the body are needed.

Germany , Hamburg , United-states , Gawarammana , Uva , Sri-lanka , Washington , San-diego , California , Antignac , Auvergne , France

Gwyneth Paltrow claims 'intuitive fasting' cured her long Covid


Gwyneth Paltrow claims 'intuitive fasting' cured her long Covid
18 minutes to read
By: Julia Llewellyn Smith
Gwyneth Paltrow has claimed that Dr Will Cole's 'intuitive fasting' system cured her of long Covid. Then again, Paltrow once thought it was a good idea to sell vagina-scented candles. So is this just another
fad diet – or might it be beneficial?
It's 8.15am in Pittsburgh, Pennsylvania, where Dr Will Cole, wellness practitioner to Gwyneth Paltrow, is talking to me from his clinic for natural medicine. Cole has been up since 6.30am. "Often I get up at 5am, but I've just back from my book launch in Los Angeles and I'm jetlagged," he explains. He's already worked out, drunk some black coffee and water and is looking forward to a cup of Earl Grey.

Germany , New-york , United-states , Brussel , Bruxelles-capitale , Belgium , United-kingdom , Israel , Italy , Pennsylvania , Canada , Switzerland

Frontiers | Ramadan Fasting Leads to Shifts in Human Gut Microbiota Structured by Dietary Composition


2School of Public Health, Lanzhou University, Lanzhou, China
3Henan Provincial Center for Disease Control and Prevention, Zhengzhou, China
The structure and diversity of human gut microbiota are directly related to diet, though less is known about the influences of ethnicity and diet-related behaviors, such as fasting (intermittent caloric restriction). In this study, we investigated whether fasting for Ramadan altered the microbiota in Chinese and Pakistani individuals. Using high-throughput 16S rRNA gene sequencing and self-reported dietary intake surveys, we determined that both the microbiota and dietary composition were significantly different with little overlap between ethnic groups. Principal Coordinate Analyses (PCoA) comparison of samples collected from both groups before and after fasting showed partial separation of microbiota related to fasting in the Pakistani group, but not in the Chinese group. Measurement of alpha diversity showed that Ramadan fasting significantly altered the coverage and ACE indices among Chinese subjects, but otherwise incurred no changes among either group. Specifically,

South-korea , Germany , Japan , Malawi , United-states , Trinidad-and-tobago , Lanzhou , Gansu , China , Italy , California , San-diego