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Renal Denervation for Resistant Hypertension Is Not Back on Track

Renal Denervation for Resistant Hypertension Is Not Back on Track
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Zapping Nerves with Ultrasound Lowers Drug-Resistant Blood Pressure

Zapping Nerves with Ultrasound Lowers Drug-Resistant Blood Pressure Brief pulses of ultrasound delivered to nerves near the kidney produced a clinically meaningful drop in blood pressure in people whose hypertension did not respond to a triple cocktail of medications, reports a new study led by researchers at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian. In a clinical trial of the procedure, called renal denervation, daytime blood pressure after two months had dropped 8 points compared to a 3-point drop in patients who were treated with a sham procedure. Nighttime blood pressure decreased by an average of 8.3 points in the treatment group versus 1.8 points in the sham group.

Pulsing Ultrasound at Kidneys Can Lower Blood Pressure When Medications Don t

Pulsing Ultrasound at Kidneys Can Lower Blood Pressure When Medications Don’t Source: Hush Naidoo/ Unsplash May 18, 2021 In about a third of all patients prescribed medications to lower elevated blood pressure (BP) levels, the drugs do not work or patients fail to take them as directed. “There are a variety of effective medications for lowering blood pressure, but many people need to take several drugs to control their hypertension, which can have side effects. In addition, many people simply don’t want to take additional medications and are poorly adherent to them,” says Ajay Kirtane, MD, professor of medicine at Columbia University Vagelos College of Physicians and Surgeons, and an interventional cardiologist at NewYork-Presbyterian/Columbia University Irving Medical Center.

Scientists find a new way to treat drug-resistant high blood pressure

Scientists find a new way to treat drug-resistant high blood pressure Credit: CC0 Public Domain In a new study from Columbia University, researchers found that brief pulses of ultrasound delivered to nerves near the kidney produced an effective drop in blood pressure in people whose hypertension did not respond to medications. In the procedure, called renal denervation, daytime blood pressure after two months had dropped 8 points compared to a 3-point drop in patients who were not treated with the procedure. Nighttime blood pressure decreased by an average of 8.3 points in the treatment group versus 1.8 points in the control group. These results suggest that renal denervation has the potential to become an important add-on to medication therapy.

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