Also this hour. The dog whos had pioneering treatment to save a leg from amputation. Scientists at Glasgow University will now begin trials to see if a newly discovered technique for regrowing bone tissue will work on humans. And at 6. 45, well have the latest on englands push for victory on the fourth day of the fourth ashes test in melbourne. Good evening and welcome to bbc news. Weather warnings are in place for parts of Northern England and scotland today after heavy snow and blizzard conditions affected large parts of the uk. Glasgow airport was closed for a few hours, with flights suspended, but has now reopened. The temperature plunged to 12c in the Scottish Highlands overnight and forecasters say driving conditions will remain difficult for the rest of the day. Judith moritz reports. Grounded at glasgow, flights at the citys airport were suspended after snow settled quickly overnight. The airport reopened by mid morning, but managers have apologised for the knock on disruption which was caused. Temperatures plummeted in scotland. Heavy snow fell in glasgow city centre, and in the highlands the mercury fell to 12 celsius. Gritters have been covering the major routes, with everyone keeping an eye on the forecast. Conditions are constantly changing at this time of the year. Even with the detailed forecasts we get, we cant always get it 100 right. In daylight, the gritting continued. Although some pennine routes were closed, the motorways remained free flowing. The snow has been falling steadily all morning across swathes of Northern England. As predicted, its been settling most in areas like this just outside huddersfield, up here on the Higher Ground. In cumbria, Hazardous Conditions left some vehicles stranded on the a590. There were also delays on other main roads. But with schools closed and many off work anyway for the holidays, disruption hasnt been too bad, and there has been plenty of opportunity for snow themed entertainment. The mayor of new york says a fire which killed 12 people at an Apartment Building in the bronx district of new york was started by a three year old child playing with a stove. The victims, including four children, died on various floors of the five storey building. Its the worst fire of its kind in the city in 25 years. The citys fire commissioner said the toddler who started the blaze was unsupervised at the time. The commissioner was speaking to reporters a little earlier last nights tragic fire, other than 9 11, was the worst loss of life from fire in our city in almost 28 years, the fire which occurred in 1990. So were in the midst right now of the worst month for loss of life in our city forfire in the past ten years. 12 people tragically died here, seven women, five men, five children, seven adults. Four other people remain hospitalised with critical injuries and are seriously fighting for their lives right now. So this fire is. I said last night, historic. It certainly is in our city, to have a loss of life like this. Fire marshals have been here all night trying to determine the cause, and they have determined it. We found that this fire started in a kitchen on the first floor. It started from a young boy, three and a half years old, playing with the burners on the stove. The fire got started, the mother was not aware of it, was alerted by the young man screaming. She exited her apartment with her two year old and three year old and left the door open. So this fire quickly spread up the stairs. Fire travels up, the stairway acted like a chimney, it took the fire so quickly upstairs that people had very little time to react, they couldnt get back down the stairs, those that tried. A few that tried perished. Others escaped, were helped out on to the fire escapes and taken down by our members. So although our members got here in a little over three minutes and bravely entered the building and did everything they could, and did save a number of residents. Theresa mays infrastructure tsar and labour peer, lord adonis, has resigned in a row over brexit. In his resignation letter, reported by the sun and the daily telegraph, lord adonis describes brexit as dangerous and claimed the Prime Minister has become the voice of the extreme right wing of her party. Lord adonis had been chair of the national infrastructire commission since april this year. He had previously served as transport secretary under gordon brown. That news hasjust transport secretary under gordon brown. That news has just come into us brown. That news has just come into us in the last hour. Lord dennis has clearly been increasingly outspoken about brexit lord adonis. In his letter, he talks about brexit as a dangerously populist decision, worthy of donald trump, despite the fa ct worthy of donald trump, despite the fact that of course, that was what britain voted for in the referendum on brexit. He is a labour peer who was appointed to head that infrastructure commission, but he has been increasingly outspoken about brexit and the governments handling of it. We understand that in his resignation letter, he says that his fundamental opposition to brexit makes it impossible for him to remain as chair of that infrastructure commission. More on that as we get it. The independent Police ComplaintsCommission Says a former Surrey Police officer who investigated jimmy savile would have faced questions of professional misconduct over his role, had he still been a serving officer. Savile, who died in 2011, was revealed to have abused hundreds of mainly women and girls. The report into Surrey Polices investigation of allegations of Sexual Offences byjimmy savile at Duncroft School in the 1970s found that the officer had failed to pass on details of an alleged indecent assault by the star at Stoke Mandeville hospital. Researchers in scotland have saved the leg of a dog using a new technique to grow bones in the laboratory. The dog, eva, would have had her leg amputated, were it not for this new approach and the treatment on her is a world first. The team from Glasgow University now wants to try the technique on humans. 0ur science correspondent pallab ghosh has this exclusive report. Theres no holding her back, but last year evas front right leg was broken in a road accident. Her vet tried everything, but nothing worked. Her entire leg was going to be amputated. She had not been able to get out for nine, ten months, other than to the toilet. But to Fiona Kirklands delight, her dog was saved by an experimental bone growing technique. It is absolutely fantastic, were so pleased to have our dog back and fit and healthy. Evas vet showed me the problem. The blood supply to the edge of the bones has failed, so it was not able to heal the break. The scientists coated the dead areas with artificial bone and afterjust six weeks, it was completely mended. The artificial bone mix was made at Glasgow University. It consists of sterilised chips that are coated with bone cells and the chemicals that make them grow, like a fertiliser. We want to look at treating more dogs and cats who have had broken bones and other areas we can help these veterinary patients, things likejoint fusion where theyve had a tendon injury sojoints can be held together to walk properly. The researchers here are so amazed at the success they have had in treating eva that they want to try out their technique on people. They plan to be the first researchers in the world to grow bone in the lab and put it into a patient in three years time. These are the people that could be most helped. It is 20 years since Princess Diana brought the issue of landmine victims to the worlds attention. Their limbs usually have to be amputated. Landmine campaigners are funding the new research so it can be used to grow some of their bone back and attach an artificial leg. If they are able to have a prosthetic limb, it would make all the difference to their life, being able to provide for the family instead of having to be a burden on the family. It has been a happy outcome for eva and her owners. Thousands of people could soon benefit from a technology that has put a spring back in her step. Earlier, i spoke to eva and her owner Fiona Kirkland and began by asking what it was like when it was feared that eva may lose her leg. She was a young dog, a dog that liked jumping and going through the undergrowth and the thought of her being on three legs, because shed already sometimes when shed been out in the garden to toilet, shed trip and fall and i had visions of a three legged dog, you know, constantly colliding with the ground. So it was quite upsetting, to be honest. At the same time, she would adapt to it, but you would rather not have to put your dog through that experience. This was after an accident shed had . Yes, she chased a fox and ended up getting hit by a car. How did you then find out about this potential new technique which eventually did save her leg . William marshall, the orthopaedic surgeon at the vet hospital, told me that this was at the point in time when normally there would be no option but to take her leg off, but because they were a Research Facility attached to Glasgow University, there was this possibility of some research that could be used to help eva. He did emphasise that it had only been used in labs at this point in time, but it was the only option for eva, otherwise she would be three legged. And we have seen those pictures of her leaping around, apparently completely sound in all four legs. How swiftly did she recover after having this treatment . Oh, it was absolutely fantastic because, you know, the accident happened injuly. Then the following march shed had this surgery and when she went back for her check up six weeks later towards the end of april, her leg was to all intents and purposes clinically healed. It wasjust phenomenal, all that time with her injured leg and then within six weeks it was healed. Having taken a risk with an untried and untested technique, how surprised were you . Surprised and very, very relieved. At the time that the research was being offered up, i didnt actually understand what was going on, what was involved in it. William had said that initially there might be a bit of a delay because the engineers were having trouble and i was thinking, is it some sort of metal that they are putting in her leg . I really didnt understand, it was only post surgery that i found out more that it was sir Bobby Charltons charity, find a better way, that funded the research and the team at the university that had been involved in devising the technique. So its absolutely brilliant for everybody, but most of all for me, evas got four legs. A pioneering dog clearly deserves every single one of those treats it must be quite something to know that she has paved the way for research that could now help humans who are suffering possibly life changing injuries . Yes, thats the whole thing about it, you know, we are delighted to have our dog with four legs again. If you just think of all those poor people whove survived landmine blast attacks, what it can do to help them, as well as other people with different types of injuries. Its phenomenal where it might all lead. Ijust cant believe it. The more i hear about it through talking with people, its wonderful for everyone. Problem with sound. Unfortunately, i think that eva might havejust had a bit of a swipe at your microphone, so we lost the end of it, but its great to see both you and eva in such good shape and i hope you enjoy many long walks together. Thanks a lot for talking to us. Thank you. The headlines on bbc news thousands of homes are without power, and roads and air travel have been disrupted after heavy snow and blizzard conditions across scotland and Northern England. Officials in new york say a fire at a block of flats in which 12 people died was caused by a three year old boy playing with a stove. Four children were among the victims. Labour peer lord adonis resigns as the governments infrastructure chief with a scathing attack on theresa may for her handling of brexit. Police say a woman found murdered in north london had been stabbed and beaten. The body of Iuliana Tudos who was 22 and originally from moscow, but had lived in london for some years was discovered on wednesday in finsbury park. Its thought she might have been attacked on christmas eve. Two men have been charged with terrorism offences by police who had been investigating a suspected christmas attack plot. 31 year old andi sami star, from chesterfield, and 22 year old farhad salah from sheffield have been detained by detectives on charges of engaging in the preparation of an act of terrorism. They appeared by video link before londons westminster magistrates court. Authorities in the indian city of mumbai have launched an inquiry, after a huge fire at an office and restaurant complex killed at least 1a people. The blaze erupted just after midnight in the popular kamala mills restaurant and shopping compound, and engulfed the structure within half an hour. Most of the victims are thought to be young women who were attending a Birthday Party. The ftse 100 has ended the year at a record high. The main index of shares listed in london ended 2017 at 7,687, up 7. 6 on last year. The Mining Sector saw the biggest gains this year while utilities such as water and electricity were the weakest. Protests are being staged across iran in whats being described as the most serious and widespread expression of public discontent in the country since disputed Election Results eight years ago. A small number of people have reportedly been arrested in the capital, tehran, and protests have since spread to other parts of the country. Earlier, i spoke to kasra naji from the Bbcs Persian Service who explained whats happening in the country. The demonstrations started yesterday in north east iran in mashhad, and it was supposed to be a demonstration against rising prices, against the government of president rouhani not being able to control these prices and the cost of living, but they quickly got out of control, the demonstrations becoming very political in nature, shouting slogans against the regime and against irans supreme leader, which we have not had for many years. The demonstrations continued today and spread to other cities, big cities around the country, and smaller towns, but let me add that these demonstrations remain small in terms of numbers, 5,000 there, 10,000 there, a few hundred there, but they remain across the country and the nature of them is very political. People are calling for the freedom of political prisoners. They are protesting against the regime, against the supreme leader, they say that the money iran is spending on wars abroad, for example, should be spent at home, wars in syria, iraq and yemen, and supportive of hezbollah in southern lebanon, so these are very political issues and many people are also shouting slogans in support of the former regime, the regime of the shah, shouting slogans demanding a return to the monarchy, if you like. At least 12 people have been killed in two separate attacks on Coptic Christians in egypt. Two shop owners were shot dead inside their premises in helwan district, south of the capital cairo. Ten people were killed in a separate gun attack on Mar Mina Church in the same district. Over the past year, more than a hundred christians have been killed in bombings and shootings in egypt. The head of the nhs in england, simon stevens, says hes considering the routine deployment of mobile alcohol recovery units, nicknamed drunk tanks, to reduce hospital admissions. Up to 70 of visits to a e departments on friday and saturday nights are linked to excessive drinking. Adina campbell reports. Binge drinking at its worst a big headache for police and a burden for the nhs. Its estimated up to 15 of attendances at Emergency Departments in the uk are alcohol related. At this time of year that number is significantly more, with as many as 70 of attendances at a e because of drinking. The uks first mobile drunk tank was introduced in bristol three years ago, and there are have been others in manchester, cardiff and newcastle. A supervised area in a city centre, it offers those who have had too much to drink a chance to be checked over by medical staff and sleep off the alcohol, keeping them away from a e or a police cell and now nhs england says it is considering routine use of the facility. We think that these facilities do have the potential to take the pressure off a e departments. Thats why they have been opened in some areas of the country. But we are interested in looking at them further and seeing the results over this winter before making a decision about rolling them out more widely. Its obviously important to reduce pressure in a e. If there are patients that we can manage elsewhere, that we find alternative services for those individuals, and this is one potential possibility. Nhs england says it is monitoring new Year Celebrations to see whether the scheme should be extended to other areas, and it will make a decision early next year. Adina campbell, bbc news. The Royal College of gps is asking patients to consider alternatives before making an appointment with their Family Doctor such as consulting websites to try to help ease the pressure on over stretched surgeries. Ben ando has the details. The season of goodwill can also be a time of bad health, and that means overcrowded surgeries, busy doctors, and a tough time for the nhs. Now the Royal College of gps is urging people to think twice and take three steps before booking a gp appointment. It wants patients to use the catchphrase three before gp meaning that in the first instance, they should try to manage their symptoms themselves. Next, they should look at reputable websites such as nhs choices. Failing that, the worried unwell should talk to pharmacists, who are better trained than many realise. Ifjust 5 of people who wanted to book an appointment today could get self help, see a pharmacist, sort themselves out by going online, actually, that would save 50,000 appointments for those who really need it. This is about using nhs resources in the best possible way, but also saving time for people as well. Doctors leaders say that for a population getting older, fatter and less healthy, there are not going to be enough doctors. They say that plans for a further 5,000 by 2021 are injeopardy. They urge the home office to add being a general practitioner to the list of those jobs which could qualify potential migrants for a fast track entry into the uk. The Royal College of gps says it thinks up to one quarter of doctor appointments could be avoided if patients were willing to take more responsibility and make a trip to the doctor a step of last resort rather than the first call they make. Apple has apologised to its customers after it admitted slowing down older iphones it says, in order to protect their batteries. The company said it would never intentionally shorten the life of any apple product, and that it will now offer replacement batteries at a discounted price. Manchester city may be running away with the premier title, but its not the only success their captain is having this year. Vincent kompany has recently graduated with an mba from Manchester Business school. His thesis was on running clubs as a business. Sean farrington met with him, and he thinks its vital that Young Players think about their career after the game. Vincent kompany, two Time Premier League winner. Fa cup winner, captain of belgium, captain of manchester city. 72 caps . 74, 75. And now master of business administration. Yeah. It feels like it was the hardest cap to come by. Being academicjust was not something for me. As you Start Talking to lawyers and accountants and the more you kind of advance, the less you understand and it was frustrating, i really hated that. And in the end, i decided i was going to put myself through studies and find out what they were talking about. I take pride because it was out of my comfort zone. I kind of felt like this was what my mother would be proud of when she passed away ten years ago. She wanted me to do well in academics. Having a hat like this isnt something you would normally see for a professional footballer still playing. I tell you what, it came by luck as well because i was looking for something i could fit into my schedule. I didnt really know what i was putting myself through. Somebody gave me this pile of books. I have no skills whatsoever. I even learned myself to type. I was typing like this. It realised it was a problem. It was more not about giving up and feeling that there is beauty in this craft, that you dont have to set yourself limits. In the end, i got something i didnt expect. Vincent kompany, the student, youve got deadlines, you are. A problem. Honestly, a few deadlines where i was travelling left, right and centre. I dont have wi fi because im in some remote corner of the world playing football. Your team mates, were they aware you were doing a masters . When i went digital, i was on my laptop like everybody else and it was easier to hide it in the very beginning, but i was getting hammered and i had to take it. It does help when you are captain of manchester city. Or it doesnt, i dont know. If you had had something as you were coming through the system as a teenager, would that help footballers more . Its a very interesting question because i think its relevant for where football will go in the next ten, 15 years. If i was heading an academy in england, i would actually say to anybody, yes, go back to school, i dont care how many hours of training he wants to do. You gain more intelligence, i can still use it on the pitch. Sounds like a message your mother would like. It is definitely a message my mother passed on. Basically, you are hearing my mother. Newly released National Archives files have revealed that Margaret Thatcher once refused to share a flight to washington with london zoos giant panda. Lord zuckerman, president of the london zoological society, suggested that chia chia the panda could share the Prime Ministers concorde flight in 1981. Washingtons Smithsonian Institution had asked to borrow chia chia, to mate it with us based ching ching. But mrs thatcher said pandas were not happy omens for politicians. Time for the latest weather prospects now. Its been an improving picture for many of us this afternoon, with plenty of sunshine around. A few showers as well, but this evening, the next batch of rain pushes up from the south west, turning to snow for the Higher Ground in wales and across Northern Ireland as it bumps into some cold air. But it will be transient snow, turning back to rain by the end of the night. It will be cold across scotland. Here, a risk of icy temperatures around freezing. Further south, much milder. That mild air will be across england and wales throughout saturday and sunday, whereas you can see the blue colours across scotland and Northern Ireland, where it remains chilly. For saturday, a windy day for all, particularly across the south and west. Outbreaks of rain across scotland, with falling snow across Higher Ground. But in between, a good slice of sunshine. It will feel very pleasant across england and wales. Cooler than that, though, further north. In many parts of the uk, with a warning of more to come. Roads were closed in a number of areas hit by snow, and theres a storm bringing heavy rain over the weekend. A huge blaze during a Birthday Party at a popular restaurant in mumbai in india kills at least 1a people. The dog whos had pioneering treatment to save a leg from amputation experts hope to use the same technique soon on people. And rain stops englands push for victory on the fourth day of the fourth ashes test