Conference this weekend and hes committed himself in principle to a ceasefire. And the 2000000 year old boy who was started to have a debate about medical ethics how much should we spend on expensive treatments especially when there are so new that its not certain will be as effective as hoped. I. Am sunni so must go on to thank you for joining us irans Supreme LeaderAyatollah Ali Khamenei has said the donald trump support for the iranian people is a pretense at fridays prayers in tehran he accuse the u. S. President of wanting to push a poison dagger into the countrys trast he also called irans airstrikes against the u. S. In retaliation for the killing of general cousin soleimani a day of got. Off the reach of National Trauma surgeons turned on. To see irans Supreme Leader in a rare show of strength i meant cheered and chanted as ali khamenei reeled against irans enemies i am. Spokesman for the wicked governments of america keep saying that we are standing with the iranian people you are lying if you do stand with the iranian people it is because you want to stick your poisoned dagger into the chest of the iranian nation you havent been able to do that so far and you wont be able to do a damn thing. His intervention comes after the countrys top military commander was killed by u. S. Forces earlier this month triggering a nationwide outpouring of grief and a tragic stampede which saw scores killed then came what iran said was an accidental dining of a passenger jet killing all 176 people on board angry protests engulfed the capital. Yet the ayatollah lamented the crash but said iran was being manipulated. Some people follow and a guided by American Television said english radio try to portray this incident in such a way that the deaths of these 2 masses would be forgotten. I dont message hared loud and clear by president rouhani who sat among the washer person the ayatollahs present underscores the crisis at the last time he delivered friday prayers in 2012 amid a standoff over its Nuclear Weapons program. For more on this story we have a theme your journalists are here with us from arabic thanks for joining us thank you for having me the last time that the Supreme Leader spoke at friday prayers was in 2012 why do you think he chose this but speak now and what do you think of what he said. Actually becoming a appeared after 80 years simply because he has to he has to address all the pressure were talking about International Pressure on the also the mystic pressure i would concentrate more on the domestic pressure because its more important for coming i think in my own opinion i mean theres anger or the winning. Of the passenger plane theres also anger over economy going to weaken situation and a sanctions theres anger over killing them so they money theres a lot of anger there so basically hes stepping in of that eightys to say im still in what im still they had because there were speculations informers about his health and also in order to say lets unite all together against the enemy the enemy now its not only the. U. S. But also its the European Union the europeans to to also theres another message for the west what they call the west its not we dont underestimate us its true that we had so many bad luck lately but also we can hit a new time and that he would when we want were still strong dont underestimate iran i think this is was the main message for the International Pressure ok so came across with a very strong message we saw although those images of the protests in iran do you think this is going to be enough to take the pressure off the Supreme Leader i will explain it very simply and then you will understand exactly how it works in iran basically its the Supreme Leader he has the main power in iran the Supreme Leader is elected by something called assembly of experts under december law comes for example the president and also members of the parliament that some feel for experts that appointed by something called the Guardian Council the guy. In council whose members are appointed by the Supreme Leader so now you can understand a little bit the power is is totally in the hands of the Supreme Leader which has come in a he has the last say when it comes to military actions he has the last say when it comes to political decisions and also economical decisions and visibly some protesters that they asked for him to step down based on some of the ports from iran they are now most of them they are in jail activists and also protesters so i dont think thats going to happen at least now its not going to happen in my opinion there are tensions in iran what can the Supreme Leader at this dude at this point to to ease those tensions especially ahead of elections in iran in february basically iran is its not playing it very hard they have think its marquis one comes to politics if i want to talk about the nuclear deal for example that they are threatening european troops through they are threatening american troops also true but also that opening the door for any negotiation now based on which terms i have no idea we have to wait and see how the negotiations behind the scenes that are going to be but also dont forget were not talking about only. Confrontation military confrontation were talking about also side but backs when it comes between iran and also the u. S. Hes concentrating the supreme deity there is concentrating on that in most mystic. Opinion now this is why we saw him today and also his opening another door for diplomacy when it comes to the west the u. S. And also the little peon so were not expecting somethings going to happen before the elections in iran soon arent the matter here from do to you arabic thank you for sharing your analysis with us thank you for having me. Lets take a look now at some of the other stories making news around the world ukraines Prime Minister all lexy one shadow cast submitted his resignation in a Facebook Post he said he had offered his resignation to president followed a missile linsky and the move comes days after hunt articles caught on tape saying the president knows nothing about the economy which i took says they were courting had been doctored doctored. More than 1100 migrants got through a Police Barrier on the border with guatemala trying to join hundreds of others heading for the Us Press Agency staff reported hundreds of people passing through a Police Cordon without going through migration protocol. Chinas economy grew last year by 6 point one percent its slowest rate in almost 3 decades its been hit by trade tensions with the u. S. And we consumer demand at home this week beijing and washington signed a pact that will reduce tariffs on u. S. Imports of chinese goods. Now to australia which after weeks of devastating bush fires is now having to cope with flash floods heavy downpours in the east have dampen down the bushfires at least for now but with more rain forecast for the coming days australians are finding themselves moving from one weather driven crisis to another i from flames to flash floods just a week ago stuff of this nature part were protecting their animals from oncoming bushfires now theyre having to deal with another extreme theres the dr who has also said absolutely inadequate you never go to the whats coming in the park a wall of water. Starts rushed koalas to safety. Back might be. Well for creatures more used to the way it was more about keeping them in their place. Heavy rain has fallen across new south wales. One of the states worst affected by bushfires in the state capital sydney residents were remembering how to use an umbrella the orange hair use that had taken over the citys skyline now cloudy grey. We need a bit of rain in order to help the 5 specially just how dry it was part of the day and i think it will help with behaves is this push everything out there this is the way to study in many many months weve only got about 4 days of running. And let run of only children. Well and truly the little spider very well. For many in the country the wet weather has brought relief and joy. More a case of sliding than singing in the rain. That rain has helped solve the north of the raging bushfires but it does bring with it another set of dangers with the land so dry and vegetation burns away water just bounces off the ground as firefighters here are well aware changing weather doesnt automatically mean changing fortunes. Now to what looks like a breakthrough in efforts to secure a truce in the civil war in libya German Foreign minister has announced that the powerful rebel leader. Has agreed in principle to abide by a cease fire the country and its backers are split between 2 rival governments one is in tripoli that is the seat of the un backed government of iraq the other is based in tobruk and this is where that this is the base of the Libyan National army which is led by general huffed are germany and the European Union are pushing for stability in libya to help stem the flow of migrants who are making the journey across the mediterranean but its a multilayered conflict and there are no easy solutions. Oh oh. Strongman general harley for hafter wants tripoli. Together with his Libyan National army he hopes to capture the countrys capital and take full control of this oil rich nation. And its partly because of oil that russia and turkey have waded in on either side of this conflict with turkey behind fires alsa rajas un backed government and russia supporting have to. Moscow has denied reports it sent to mercenaries to reinforce the generals fighters but on thursday turkey confirmed it had started deploying troops to help in tripoli despite a un arms embargo. With libyas so unstable the fear of resurgent islamist terror has worried many European Countries but other factors mean the e. U. Is split over its alliances. Officially the tripoli based government has the backing of europe including germany but italy has openly supported general haftar who it sees as crucial in stemming the flow of migrants across the mediterranean and frances concerns over terrorism as well as its interests in libyas oil wealth has pushed towards with the e. U. s official line there are claims its given Covert Military help to general hafta earlier this week peace talks in moscow broke down. Despite the many interests at stake and the players involved germany seems determined to pursue its mediation role. Which even if a ceasefire is agreed the road to peace looks long and bumpy. While the libyan ceasefire talks are taking place here in berlin on sunday will of course be there to bring you all the latest developments still to come here on news it is fashion week here in berlin and someones come up with a new way of recycling jeans yes they really are being shredded well tell you why. But 1st Pharmaceutical Company no vargas has announced it will use a lottery to supply the worlds most expensive drug to children suffering from a devastating genetic disease called spinal Muscular Atrophy but only 100. 00 Children Worldwide will receive the free treatment which usually costs millions of dollars the astronomical price of such drugs has triggered an ethical debate. Story sounds like a modern fairy tale but it also poses questions. He was born with spinal Muscular Atrophy a life threatening neuromuscular disease when his condition deteriorated despite treatment his family launched an Online Fundraising campaign. For him to receive a gene therapy thats not licensed in europe yet gets the help if it was. A treatment cost almost 2000000 euros professional athletes and celebrities lead their support bowing to pressure from the Public HealthInsurance Company agreed to pay michael received the most expensive therapy in the world. But that. Only grew thinner and as it was a miracle that it worked at all then on the 3rd day we had another miracle wonder that he could turn himself over properly and in the 2nd week he even sat up on his own. The joint was shared by very many online supporters but there are other opinions about the treatment. Some say not enough tests have been done to guarantee its safety more parents have been demanding access to it Health Authorities are sounding the alarm. This is about our promise over healing thats and i really hope its one that will be for velvet but we still dont know if it will be and so this is a game of hope of one happening outside the normal system so its not how we should be doing things to. The manufacturer and novartis has issued a statement on its product the decision to implement the therapy must be made by specialized doctors under careful consideration of the risks on an individual basis and we are prepared to offer financial concessions to Insurance Companies. But this Case Highlights another major question in a Public SectorHealth Care System how much may the treatment cost many expensive gene therapies are set to gain market approval in the coming years what kind of results justify what kinds of costs at the University Hospital in bonn dr youn band kirshner meets families who have the prescription that costs 2000000 euros he says it doesnt make sense yet to start prescribing the therapy on a wider scale i think its one of the. Very new kinds of therapies where were not sure how effective or safe they are we need consensus between all parties between specialist doctors experts centers Insurance Companies and licensing authorities only then can we properly decide which patients we should treat with a therapy thats at such an early stage. Michael seems to be doing well so far although no one knows if the 2000000 euro medication has really healed his disease for good still his story shows how vital it is to regulate costly new gene therapy. A story that raises a lot of questions that were going to talk about with our science reporter williams and our religious Affairs Correspondent martin guy good to have you both here in our studio durcan to start with you can you explain how this treatment actually works well this is a completely different kind of treatment than generally comes out of the pharmaceutical industry this is a treatment and healing a genetic disorder not genetic disorders cause mean if you have a genetic disorder its down to a faulty gene which isnt producing a particular protein correctly and the lack of that protein can have a greater or lesser impact on your health now what this these kinds of treatments do gene therapy treatments do is they replace that faulty gene with an intact copy of the gene and they do that using viruses they enjoy inject viruses into your body which are able to enter the cells and add themselves to your d. N. A. So that from that point on your cells have an intact copy of the d. N. A. And they can produce the protein properly now so ultimately what that means is that this is at least in theory a one shot treatment that heals it after that your body continues to make the protein properly in your diet and your condition is taken care of and it seemed to be effective at least short term it hasnt been around for that long the question is whether or not it really is going to last forever whether its going to be or if theres going to have to be theyre going to have to be booster shots along the way thats one of the Big Questions actually in this debate right and theyre also ethical questions that this gene therapy it raises i mean what do you think the biggest ethical concerns are here me usually one of the biggest issues that we have is that we are facing other misstating illness that affects children intuitively one would see this and immediately sort of you know removed the same time we have. A drug that costs essentially a small fortune for a bar and or for a country for Health System to actually the ploy so i think that at the forefront of the discussion its a question. Access to medicine and access to cures especially in light of new technologies that is a question derek that people are asking specifically of this harm cynical company why does this therapy cost so much money well you have to its not its not only no vargas its a question of the pharmaceutical industry the Business Model that its based on its not based on giving us one shot treatments that heal us the fall pharmaceutical industry is based around Health Care Management its based around producing drugs that then continues to possibly sell you for the rest of your life that will eventually allow them to recoup the cost and compensate them for the work that they put into that into the research and development of that particular drug you cant forget that the research and development for every 10 drugs that are that are that are in testing only one drug will actually make it through to the end in fact the pharmaceutical industry says that each and every drug that gets develops nowadays costs upwards of 2000000000. 00 euros in Development Cost before its actually on the market so theres that aspect of it and they say that we have to recoup those costs in order to drive further innovation is that there were sponsibility market well its actually a very good question its one that i dont think can be solved by a Single Person sort of making moral or making scientific claims the one thing that i think we should be warned about particularly because of the hero from a Studio Company is that the claims about the cost of development should not be taken at face value a few days true that were all being called to participate in essentially supporting the companies that are developing the slave saving cures then it is important that we see that as a matter of fact these are the costs of state at the very same time there is a 2nd argument that is very usually the bloated buy buy from Suitable Companies which is that they are not charge hes not only they have to recuperate the cost of the relevant but as a matter of fact they are in the business of making money and i think that this is sort of a problem that is certainly a major ethical problem with this drug because of the pricing and illness that it attacks but its of questions i think that more broadly put to the pharmaceutical industry i think that children are have an intuitive and under. Standing off the fact that we should not be in the business of taking advantage of people in a position of suffering and when we have an industry that pretty creates a Business Model on the idea that bruff it is going to be extracted directly for people that are in a situation of suffering i think that we face mean a 1000000 at the go dilemma if in fact we have a moral dilemma for most people they would say there is no the limit although its very clear that this is wrong in this case sorry were talking about dead children to put it in a way that maybe 6 plosive but i mean i really want to conjure the mage so that stage the question becomes either a lot more complicated or a lot simpler the ending where you stand i think well i think the position medicine which is what this field particularly is is really causing us to ask basic fundamental questions about the monetization of health care in general i mean. A pharmaceutical product a medicine thats potentially lifesaving its not a product in the sense that we would think of say an i phone we have to but we still treat it in that way economically and in the Business World its a business its its about making money and the question is is that system has been in place for a very very long time monetizing health care but i think that precision therapies like this one are really going to have to force us to question that as we move forward into the future where this is not the only drug that this is happening with there are 5 that have been approved so far and there are dozens more in the pipeline and theyre all going to want to be charging a couple of 1000000. 00 or a couple of 1000000 euros for a single shot treatment and so the question is how do we deal with that both as a society and as a Public Health care and the Public Health care sector is really doesnt help is this immaterial that they are now offering 100 free injections of this specific therapy to children are affected but based on a lot of resets i mean is that the right way to go about it but i think i mean its quite simply no i mean clearly no you know that the basic problem is one that again i think that its mostly intuitive 1st people that look at it from a certain distance lotteries are against the death of children or. No and when youre actually sort of formulating the blame and life saving methods in those terms i mean youre engaging in a pretty sinister game so i mean what youre basically saying is buy the ticket or take the ticket if you get the price your child is safe if not tough luck certainly i think that behind these i have to assume that there is a Good Intention which is actually to the 100 of these cures for free and then of course the question is how we said that we affected really blow this resource but in my estimation. Is a very good indicator of the very broken them which is if this is going to be presented as something that can only be selectively the ploy. Then as a matter of fact its very likely that were not going to one to see 2000000. 00 or thereabout sort of the very year for actually acquiring the drug its actually interesting to just one more quick the companies that are selling these drugs theyre actually selling them as a cheap alternative to conventional medicines theyre saying conventional medicines to treat the symptoms of the patients that might have this will cost over the course of 10 years 5000000 dollars and were selling it for 2 so its actually a bargain really interesting discussion guys that i think that with us here in studio and Eric Williams thank you both youre welcome. Now its a berlin fashion week a time and place for Young Designers to earn their stripes and theyve been tapping into the mentality and aesthetics of millennial generation the which means the same ability is increasingly important in their product lines. Sustainability can be pretty sure some of the environmentally friendly fashions on display or even runway ready sustainable style has moved on from the crunchy granola look of the past that the neon lit the berlin trade figure for sustainable fashion the focus is on where ability and the basics of the berlin label bloops this restore blood sisters hasnt sacrificed style in their pursuit of more ecological fashion but changing the industry will take time. Of course everything goes step by step initially people would say to us your clothes we have your trade but youre not using organic cotton so many facts wrong is slowly catching up that weve been working with manufacturers in india and china and are also trying to get them to implement fair working conditions you can expect them to immediately be able to produce arcana cotton. Cloth. A dutch jeans maker is taking a different route with my jeans you dont buy the jeans you want them for 7 year olds 50 a month if you return them within a year the jeans are shredded and then recycle. Them as ive been since my we make new jeans out of old jeans we shred the your genes to make yarn i combined with new organic cotton to make the fabric for our new jeans up and. Recycling is the sustainability trend of the new. Old balls turned into new handbags. And shoes using renewable materials like cork or to make the big fat souls of these punks cauthen techno kloppers recycled plastic. These spanish sneakers will run you 200. 00 euros sustainability doesnt come cheap studies however show that fully a 3rd of all purchased clothes are never even worn so maybe the solution is to buy fewer more expensive clothes that last longer. A reminder now of our top story irans Supreme Leader has returned to his attack on the u. S. Ayatollah ali khamenei has told the crowd of friday prayers in tehran that President Trump want to push a poison dagger into irans trust. Youre watching g. W. News coming up next our health and wellness show in good shape state of. What keeps us in shape what makes us see. My name is dr khan. I talked to medical experts. Watch them at work. And they discuss what you can do to improve your head. Stay tuned and lets all try to stay. Good chinks next on the. Board. Grappling with subjects. Expressing feelings i am not very free of yet but i would love to be considered an artist one day looking for new perspectives on the haitink noted with a reply whose breakthrough via camera doing things differently. Come to the place where we reflect on society. March 21 to talk to w. Can i am back and. Stick closest place to hell i was listening to him standing kiran. And gangsters a camp. All net trains kimi and more ignorant than you. Nicias and he didnt want to marry. Mom. Malegaon story. Nikos a. Must. Start in january 27th on d w. She. Welcomes are you in good shape coming up. Fitness training for core muscles. Might therapy special maps for seasonal depression. And