GWAS Reveals Multiple Host Genes Linked to Severe COVID-19 Symptoms

GWAS Reveals Multiple Host Genes Linked to Severe COVID-19 Symptoms
July 9, 2021
A global initiative founded in March 2020 called the COVID-19 Host Genomics Initiative has released a comprehensive summary of their findings, which reveal 13 loci in the human genome that are strongly associated with infection or severe COVID-19. The researchers also identified causal factors such as smoking and high body mass index. The results, published in
Nature, come from one of the largest genome-wide association studies (GWAS) ever performed, which includes nearly 50,000 COVID-19 patients and two million uninfected controls. The findings could help provide targets for future therapies and illustrate the power of genetic studies in learning more about infectious disease.

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