mRNA vaccine reprograms immune system to attack glioblastoma

An mRNA cancer vaccine developed at University of Florida may have the ability to reprogram the immune system against glioblastoma, findings of a first-in-human trial showed.The trial — results of which appeared in Cell— included four adults with immunotherapy-resistant MGMT unmethylated glioblastoma.

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Elias Sayour ,Byjennifer Byrne ,Mindy Valcarcel ,Eliasj Sayour ,University Of Florida Prestona Wells Jr ,University Of Florida ,Uf Health Cancer Center ,Mcknight Brain Institute ,Engineering Laboratory ,Brain Tumor Therapy ,Cancer Center ,