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Torino, February 24, 2021 - The eukaryotic cell is the basic unit of animals and plants. At the microscope, it looks highly structured and subdivided in many membrane-bound compartments. Each compartment has a specific function, and its membrane is populated by specific molecules. How does the cell preserve this amazing internal order, and (in the absence of pathologies) does not degrade into a shapeless bunch of molecules? Such degradation is countered by a continuous process of molecule sorting by which similar molecules are collected and dispatched to the "right" destinations, similarly to what happens when a house is kept clean and tidy by daily chores. It's still mysterious, however, how a living cell may achieve this task without a supervisor directing it.