Revolutionizing drug discovery: The role of CRISPR gene editing in target validation

Target validation is a crucial step in pre-clinical drug discovery workflows that builds confidence on the identification of a genetic target as relevant to a disease. With recent advancements, CRISPR serves as a particularly powerful tool for this process, as it enables researchers to accurately modify genes and determine their function in a variety of experimental systems.

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Sergio Casas ,Rinki Ratnapriya ,Yu Holly Chen ,Krishanu Saha ,Panos Zalmas ,Head Of The Open Targets Validation Lab ,Wellcome Sanger Institute ,University Of Wisconsin ,Institute For Rare Diseases Research ,Validation Lab ,Baylor College Of Medicine ,University Of Alabama At Birmingham ,Editorial Article ,Open Targets Validation Lab ,Genome Editor ,Thermo Fisher Scientific ,Baylor College ,Sergio Casas Tint ,Drosophila Models ,Human Disease Unit ,Rare Diseases Research ,