1. 92.4% of children in high-income countries had heterozygous familial hypercholesterolemia compared to 48.0% in non-high-income countries. 2. The majority of patients with confirmed heterozygous familial hypercholesterolemia were not on any lipid-lowering medication. Evidence Rating Level: 2 (Good) Study Rundown: Familial hypercholesterolemia affects more than 450,000 children worldwide each year, yet only a small proportion