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AACR Meeting News: Synlogic Presents Encouraging Data on Immunotherapy Drug

Nivolumab Alone Prevails in Resected Melanoma

email article Dual checkpoint blockade with nivolumab (Opdivo) plus ipilimumab (Yervoy) failed to improve outcomes as adjuvant therapy for resected melanoma over nivolumab alone, the CheckMate 915 trial found. In the intent-to-treat (ITT) population of more than 1,800 patients with stage IIIB-D/IV melanoma, relapse-free survival (RFS) at 2 years was nearly identical with the combination versus single-agent PD-1 blockade with nivolumab, at 64.6% and 63.2%, respectively (HR 0.92, 95% CI 0.77-1.09), reported Georgina Long, MBBS, PhD, of the University of Sydney. In the subset with low PD-L1 expression (

Instil Bio Presents Clinical Data in Metastatic Melanoma in a Late-Breaking e-Poster at the

Press release content from Globe Newswire. The AP news staff was not involved in its creation. Instil Bio Presents Clinical Data in Metastatic Melanoma in a Late-Breaking e-Poster at the . Instil BioApril 12, 2021 GMT 67% overall response rate and 19% complete response rate in 21 patients All complete responders remained in remission at time of data cut-off DALLAS, April 12, 2021 (GLOBE NEWSWIRE) Instil Bio, Inc. (“Instil”) (Nasdaq: TIL), a clinical-stage biopharmaceutical company focused on developing tumor infiltrating lymphocyte, or TIL, therapies for the treatment of patients with cancer, presented clinical data from a compassionate use program for the treatment of metastatic melanoma at the American Association for Cancer Research (AACR) virtual meeting April 10 – 15, 2021. The presentation abstract and additional information is available on the AACR conference web site at www.aacr.org.

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