Three of the trials did not have study acronyms (only trial registration numbers) and ILBS-COVID-02 and PLACID did not have expansions in the original publications. ConCOVID indicates Convalescent Plasma as Therapy for Covid-19 Severe SARS-CoV-2 Disease; ConPlas-19, Convalescent Plasma Therapy vs SOC for the Treatment of COVID-19 in Hospitalized Patients; NA, not available; PICP19, Passive Immunization With Convalescent Plasma in Severe COVID-19 Disease; PlasmAr, Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia; RECOVERY, Randomized Evaluation of COVID-19 Therapy.
aThere was no detailed information reported regarding (1) the randomization process or (2) the concealment of randomized assignment.
bThere was no detailed information reported regarding (1) the randomization process, (2) the concealment of randomized assignment, (3) the flow of patients through the trial, and (4) possible deviations from the intended interventions due to the open-label setti
KTH researchers identify 300 proteins that regulate cell division process news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
Liver transplantation is currently the only treatment available for the severe liver disease PSC. Now, however, researchers at Karolinska Institutet and.
E-Mail
IMAGE: A montage of microscopic images that show the stages of the cell cycle, in which a single cell duplicates its DNA and eventually divides into two daughter cells. Staining shows. view more
Credit: KTH Royal Institute of Technology/SciLifeLab
With the hope of contributing to the fight against cancer, researchers in Sweden have published a new molecular mapping of proteins that regulate the cell division process - identifying 300 such proteins.
The release of the data, which was published today in the scientific journal,
Nature, is significant because it helps bring medical research closer to the point of being able to target specific proteins to treat cancer.
E-Mail
A toxin produced by bacteria as a defence mechanism causes mutations in target bacteria that could help them survive, according to a study published today in
eLife.
The finding suggests that competitive encounters between bacterial cells could have profound consequences on the evolution of bacterial populations.
When bacterial cells come into contact, they often produce toxins as a defence mechanism. Although it is known that the bacteria producing these toxins have a competitive advantage, exactly how the toxins affect the recipient cells is less clear. Undergoing intoxication is not always detrimental for cells - there are scenarios in which encountering a toxin could provide a benefit, such as generating antibiotic resistance, explains lead author Marcos de Moraes, Postdoctoral Scholar at the University of Washington School of Medicine, Seattle, US. We wanted to study the effects of a toxin that alters DNA beyond that of cell death and see how it impacts the surv