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Cholesterol-Lowering Statins May Protect Against Heart Damage From Chemotherapy Drugs, Study Finds

January 5, 2021 Terry Matthews/Alamy; Everyday Health Statins may have protective benefits for the heart in women undergoing chemotherapy treatment for early breast cancer, new research suggests. Women on the cholesterol-lowering medications were significantly less likely to visit the emergency room or to be hospitalized from heart failure when on certain chemotherapy drugs than their counterparts who were not taking statins. The results were published in January 2021 in the . The study looked at anthracyclines and trastuzumab, two types of cancer medications commonly used to treat breast cancer. While these medications are effective at killing cancer cells, they can also damage the cells of the heart muscle, leading to a weakening of the heart and increasing the risk of heart failure.

Statins May Shield Hearts From Damage Caused by Breast Cancer Chemotherapy

Read Time: New research from UHN s Peter Munk Cardiac Centre (PMCC) shows statins, commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also protect the heart from damaging side-effects of early breast cancer treatment. Published Jan. 6, 2021 in the  Journal of the American Heart Association, an observational study found women already taking statins and treated with either anthracyclines or trastuzumab were half as likely to be hospitalized or visit an Emergency Department for heart failure within five years after chemotherapy. Our job is to protect the heart and ensure it has the greatest fighting chance to get through chemotherapy, says Dr. Husam Abdel-Qadir, lead author of the paper and a cardiologist at the PMCC and Women s College Hospital. He notes prior observational studies have reported measures of heart strength in statin-treated women after chemotherapy, but only focused on a single centre.

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