Published: Feb 04, 2021 By Alex Keown
China’s JW Therapeutics, which was co-founded by Juno Therapeutics and Wuxi AppTec, forged a partnership with Thermo Fisher Scientific to ensure non-exclusive
commercial access to Thermo Fisher’s Gibco CTS Dynabeads CD3/CD28. The exclusive agreement will be used to support JW’s clinical development programs for CAR-T (Chimeric Antigen Receptor T-Cells) therapies in China. The deal includes JW Therapeutics’ lead product relmacabtagene
autoleucel (relma-cel), which is an anti-CD19 CAR-T therapy for third-line treatment for relapsed or refractory B-cell lymphoma. The therapy’s new drug application has been accepted by China s National Medical Products Administration. Relma-cel is expected to be the first CAR-T therapy to be approved as a Category 1 biologics product in China.
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Bitcoin Vigilantes
Market Recap
Anticipating strong economic and earnings gains in 2021 after the COVID-inspired recession in 2020, broad stock indices continued their hefty rally in 2020’s fourth quarter. I believe resolved political, economic, tax, and virus uncertainties inspired investors to the riskier, cyclical, and ignored parts of the market like small-caps (Russell 2000 up 31%) and value (Russell Large Value 16.2%).
From the March 23rd, 2020 lows to January 8th, the S&P 500 and NASDAQ are up 70.9% and 92.4%, respectively, reaching record highs. Historically, increased visibility/less uncertainty has provided fuel to markets as it is easier to make business decisions and model cash flows.
To this end, moderate Democrat Joe Biden has begun his peaceful transition to the White House and will lead a unified Democratic Congress, likely leading to additional fiscal stimulus, a greater push towards green infrastructure/energy, and potentially higher taxes.