ஏற்ற சினை மனிதன் நோய் எதிர்ப்பு சக்தி கண்காணிப்பு மையம் News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Early-stage lung cancer coopts macrophages to help tumors invade lung tissues

Early-stage lung cancer coopts macrophages to help tumors invade lung tissues Immune cells that normally repair tissues in the body can be fooled by tumors when cancer starts forming in the lungs and instead help the tumor become invasive, according to a surprising discovery reported by Mount Sinai scientists in Nature in June. The researchers found that early-stage lung cancer tumors coopt the immune cells, known as tissue-resident macrophages, to help invade lung tissue. They also mapped out the process, or program, of how the macrophages allows a tumor to hurt the tissues the macrophage normally repairs. This process allows the tumor to hide from the immune system and proliferate into later, deadly stages of cancer.

Miriam meradEmily hendersonHuman immune monitoring centerMount sinai human immune monitoring centerIcahn school of medicine at mount sinaiPrecision immunology instituteMember of the institute thoracic oncologyInstitute of thoracic oncologyTisch cancer institute at mount sinaiMount sinaiIcahn schoolThoracic oncologyTisch cancer instituteஎமிலி ஹென்டர்சன்மனிதன் நோய் எதிர்ப்பு சக்தி கண்காணிப்பு மையம்ஏற்ற சினை மனிதன் நோய் எதிர்ப்பு சக்தி கண்காணிப்பு மையம்

Early Lung Cancer Coopts Immune Cell Into Helping Tumors Invade the Lungs, Mount Sinai Researchers Discover

Early Lung Cancer Coopts Immune Cell Into Helping Tumors Invade the Lungs, Mount Sinai Researchers Discover
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New yorkUnited statesLong islandMiriam meradHealth systemTisch cancer institute at mount sinaiHuman immune monitoring centerMount sinai human immune monitoring centerIcahn school of medicine at mount sinaiPrecision immunology instituteMount sinai health systemIcahn school of medicineInstitute of thoracic oncologyMount sinaiIcahn schoolThoracic oncology

Early lung cancer coopts immune cell into helping tumors invade the lungs

Early lung cancer coopts immune cell into helping tumors invade the lungs
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Researchers identify cause and drug targets for bewildering rare children s disease

E-Mail New York, NY (May 6, 2021) Researchers have finally cracked the code of a bewildering pediatric disease that sets off a characteristic cytokine storm a harmful immune system overaction resembling one that arises in COVID-19 cases and can lead to catastrophic multisystem organ failure or neurodegeneration. Their study, which identifies the cause of the cytokine storm and possible treatments, was published in Nature Medicine in May. The mystery of this disease, Langerhans-cell histiocytosis (LCH), runs deep. Its symptoms vary widely, and LCH has the ability to infiltrate almost any organ system, leaving most patients with long-term consequences that may include a devastating neurodegenerative syndrome that can arise years after other symptoms have abated.

New yorkUnited statesLong islandMatthias wilkMiriam meradCarl allenHealth systemTisch cancer institute at mount sinaiMount sinai human immune monitoring centerProfessor of oncological sciencesIcahn school of medicine at mount sinaiPrecision immunology instituteMount sinai health systemIcahn school of medicineNature medicineMount sinai