Dec 18, 2020
Treatment approach has potential disease-free survival advantage
Patients with locally advanced rectal cancer treated with total neoadjuvant therapy followed by surgery had a higher chance of achieving a pathologic complete response than those treated with standard therapy involving concurrent chemotherapy followed by surgery and adjuvant chemotherapy, a meta-analysis of 7 trials involving more than 2,400 patients revealed.
The pooled prevalence of pathologic complete response (PCR) was 29.9% in the total neoadjuvant therapy (TNT) patients and 14.9% in the standard treatment group.
Surgical outcomes, including rates of sphincter-preserving surgery and ileostomy, did not differ significantly between the two treatment groups, and just 3 studies included data on disease-free survival while none included data on overall survival.
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From her son, Joe Hepplerâs room at Kansas University Medical Center, Cathy Heppler put her cellphone on speaker so she had both hands available to consult her notes.
âWe have been in the hospital this time 77 days so far, which makes 122 days for the whole year.
âThis is the fifth infection he has had in his brain this year,â Heppler said Tuesday. âThis would be our fourth trip of the year up here.â
Joe has had 16 surgeries this year and battled five different bacterias in his brain.
The latest and worst brain infection led Joeâs hospitalization on Sept. 29 at KUMC. Since Sept. 29, he has had six brain or shunt-type surgeries.Â
With death of 28-year-old man, 3 people now have died following house explosion in Omaha kearneyhub.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kearneyhub.com Daily Mail and Mail on Sunday newspapers.
By Julia Bertino
Dec 10, 2020
One of the men critically injured in a Tuesday morning home explosion in South Omaha has died.
Omaha Police say 28 year old Alexander Toledo died on Wednesday at the Kansas University Medical Center in Kansas City, Kansas. Police say Toledo had been transferred to the Kansas hospital shortly after the explosion for further treatment.
Also killed in the explosion were Alexander s grandmother 73 year old Theresa Toledo, the home s owner, and Alexander s mother 45 year old Angela Miller. Police say another man, 72 year old Larry Rodriguez, was also critically injured in the blast. He remains hospitalized at Nebraska Medicine.