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Researchers identify potent small molecule TMPRSS2 inhibitor against SARS-CoV-2
A team of scientists from the USA and Canada has recently identified and characterized a novel small-molecule compound inhibitor of cellular serine protease TMPRSS2, which shows significant antiviral potency against emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study by researchers from the University of British Columbia, Cornell University College of Veterinary Medicine, and Université de Sherbrooke is currently available on the
Background
As of today, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), has infected more than 154 million people and claimed 3.23 million lives globally. The approval and widespread distribution of several highly effective vaccines, along with other public health measures, now allows the possibility of controlling the COVID-19 pandemic. However, novel gene