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Hypofractionated ablative radiation therapy (RT) following standard chemotherapy was associated with durable tumor control and impressive survival outcomes for patients with locally advanced, inoperable pancreatic cancer in a retrospective single-center study.
From 2016 to 2019, median overall survival (OS) in more than 100 patients receiving ablative RT at a biologically effective dose of 98 Gy reached 18.4 months from the time of RT and 26.8 months from the time of initial diagnosis, reported Christopher Crane, MD, and colleagues from Memorial Sloan Kettering Cancer Center in New York City.
The 1- and 2-year OS rates from the time of ablative RT were 74% (95% CI 66-83%) and 38% (95% CI 27-52%), according to the findings in