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Established in 2019 in Nashville, COMBINEDBrain is a non-profit consortium of patient advocacy groups, researchers and clinicians working together to fast-track cures and therapies for individuals afflicted with rare genetic neurodevelopmental disorders.
Established in 2017, the Marlene and Spencer Hays Foundation has a mission to support efforts to improve peoples lives through the arts; research and innovations in health care; education and programs to help at-risk youth; and to promote enhanced economic achievement by encouraging discipline, ambition and commitment to goals and principles.
Fulfilling the goal of promoting innovations in health care, The Marlene and Spencer Hays Foundation awarded COMBINEDBrain a grant of $68,000 which will be used for operating expenses to support 21 patient advocacy organizations prepare for clinical trials. Each of these member organizations is run by dedicated parents, seeking solutions for their children and others around the wor
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Researchers have shown that the link between physical and mental illness is closer than previously thought. Certain changes in physical health, which are detectable in childhood, are linked with the development of mental illness in adulthood.
The researchers, led by the University of Cambridge, used a sample of over 10,000 people to study how insulin levels and body mass index (BMI) in childhood may be linked with depression and psychosis in young adulthood.
They found that persistently high insulin levels from mid-childhood were linked with a higher chance of developing psychosis in adulthood. In addition, they found that an increase in BMI around the onset of puberty, was linked with a higher chance of developing depression in adulthood, particularly in girls. The results were consistent after adjusting for a range of other possible factors.
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A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.
The discovery, published in the
Journal of Neuroimmunology, could be important in treating or preventing the progression of multiple sclerosis and other central nervous system disorders. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin. Sobetirome and related drugs are effective at stimulating myelin repair after damage has occurred. Our new findings now suggest that these drugs could also prove to be beneficial for preventing damage from occurring, said senior author Dennis Bourdette, M.D., former chair and professor emeritus of neurology in the OHSU School of Medicine. It means that these drugs have a dual effect that we didn t know about before.
What percent of patients with Alzheimer s Disease (AD) currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study (FHS) sheds light on these trends.
A new study from UBC researchers suggests a strong correlation between following the MIND and Mediterranean diets and later onset of Parkinson s disease (PD). While researchers have long known of neuroprotective effects of the MIND diet for diseases like Alzheimer s and dementia, this study is the first to suggest a link between this diet and brain health for Parkinson s disease (PD).