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IMAGE: A night shift schedule is associated with increased DNA damage and misalignment of the DNA repair mechanism, providing a possible explanation for the elevated risk of cancer in night shift. view more
Credit: Bala Koritala
SPOKANE, Wash. - New clues as to why night shift workers are at increased risk of developing certain types of cancer are presented in a new study conducted at Washington State University Health Sciences Spokane.
Journal of Pineal Research, the study involved a controlled laboratory experiment that used healthy volunteers who were on simulated night shift or day shift schedules. Findings from the study suggest that night shifts disrupt natural 24-hour rhythms in the activity of certain cancer-related genes, making night shift workers more vulnerable to damage to their DNA while at the same time causing the body s DNA repair mechanisms to be mistimed to deal with that damage.
Research from Queen Mary University of London has concluded that there is convincing evidence that type 2 diabetes is associated with an increased risk of Parkinson s disease. The same study found that there was also evidence that type 2 diabetes may contribute to faster disease progression in patients who already have Parkinson s.
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IMAGE: Dr. Wylie, director of the Rocco Ortenzio Neuroimaging Center at Kessler Foundation, specializes in the implementation of neuroimaging techniques in rehabilitation research. view more
Credit: Kessler Foundation
East Hanover, NJ. March 8, 2021. Kessler Foundation researchers have demonstrated changes in the functional connectivity within the fatigue network in response to cognitive fatigue. This finding, the first of its kind, was reported in
Scientific Reports on December 14, 2020 in the open access article, Using functional connectivity changes associated with cognitive fatigue to delineate a fatigue network (doi: 10.1038//s41598-020-78768-3).
The authors are Glenn Wylie, DPhil, Brian Yao, PhD, Helen M. Genova, PhD, Michele H. Chen, PhD, and John DeLuca, PhD, of Kessler Foundation. All have faculty appointments at Rutgers New Jersey Medical School. Dr. Wylie is also a research scientist at The Department of Veterans Affairs War-related Injury a
Odors evoke powerful memories, an experience enshrined in literature by Marcel Proust and his beloved madeleine. A new paper is the first to identify a neural basis for how the brain enables odors to so powerfully elicit those memories. The paper shows unique connectivity between the hippocampus the seat of memory in the brain and olfactory areas in humans. It s like a superhighway from smell to the hippocampus.