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Yale neurologists identify consistent neuroinflammatory response in ICH patients

 E-Mail Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease. However, up until now, there has been limited information on inflammation in the brain from human patients, especially during the first days after a hemorrhagic stroke. This led a team of researchers to partner with a large clinical trial of minimally-invasive surgery to tackle defining the human neuroinflammatory response in living patients. Our goal was to find out, for the first time, how certain key cells of the immune system are activated when they enter the brain after a hemorrhage and how this may shift over the first week. This is a critical time for our patients, said Lauren Sansing, MD, Academic Chief of Stroke and Vascular Neurology and Associate Professor of Neurology and Immunobiology at Yale.

Sleep is vital to associating emotion with memory, according to U-M study

Distorting memories helps the brain remember

Credit: Zhao et al., JNeurosci 2021. In order to remember similar events, the brain exaggerates the difference between them. This results in divergent brain activity patterns but better memory performance, according to new research published in JNeurosci. Memory is subjective. Different people recall the same event in unique ways, and people exaggerate the difference between similar events in their own life. Yet this type of bias can be advantageous when it helps the brain distinguish between similar things and prevent confusion. In a study by Zhao et al., participants memorized different sets of faces paired with colored objects. Some objects were identical except for slight color differences. At the start of training, the participants had a hard time distinguishing pairs when the objects were almost identical. However, after two days of practice and testing, performance improved. Participants were then shown a face and imagined the corresponding object while the researchers me

Yale scientists repair injured spinal cord using patients own stem cells

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