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El investigador de la UGR Carlos Peris, finalista de Famelap España 2021
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Scientists and clinicians at UCL and Great Ormond Street Hospital (GOSH) studying the effectiveness of CAR T-cell therapies in children with leukaemia, have discovered a small sub-set of T-cells that are likely to play a key role in whether the treatment is successful.
Researchers say stem cell memory T-cells appear critical in both destroying the cancer at the outset and for long term immune surveillance and exploiting this quality could improve the design and performance of CAR T therapies.
Explaining the study, published in
Nature Cancer, lead author Dr Luca Biasco (UCL Great Ormond Street Institute of Child Health), said: During clinical trials we have seen some very encouraging results in young patients with leukaemia, however it s still not clear why CAR T-cells continue to be present in the long-term for some patients, stopping the cancer from returning, while others remain at a high risk of relapse.
Updated:
May 23, 2021 01:55 IST
What is the view of experts on immunisation against COVID-19 for these sections, and where does India stand?
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What is the view of experts on immunisation against COVID-19 for these sections, and where does India stand?
The story so far
: Over four months after the COVID-19 vaccination drive was launched, India has administered around 19 crore doses of Covishield and Covaxin so far. But it is yet to open up vaccination for pregnant women and children. On May 19, the Union Ministry of Health and Family Welfare accepted fresh recommendations from the National Expert Group on Vaccine Administration for COVID-19 (NEGVAC) for vaccinating lactating mothers. The country is yet to study the safety and efficacy of the two existing vaccines in the paediatric population, with the Drugs Controller General of India recently giving the nod to Bharat Biotech to conduct clinical trials of Covaxin in the 2-18 years age group.
More newborns show symptoms
Updated:
Updated:
1%-2% develop significant symptoms of cough and require admission
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1%-2% develop significant symptoms of cough and require admission COVID-19 cases among the paediatric population has been on the rise in Tamil Nadu. Doctors have been noticing that more newborns are presenting with symptoms during the second wave of the contagion than in the first wave.
At least 1,000-1,300 children, aged 0-12, are testing positive daily over the past few days. “The number of children testing positive is quite high. When parents test positive, the children, too, are infected,” said S. Srinivasan, State Nodal Officer-Child Health.
Our governance - UK National Screening Committee
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