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New research on good cholesterol possibly finds better marker for cardiovascular disease

Credit: Ulf Sirborn Good cholesterol, which is transported in HDLs (high-density lipoproteins), plays a key part in the prevention of atherosclerosis and thus the risk of cardiovascular disease. However, according to a new paper co-authored by researchers at Karolinska Institutet in Sweden and published in the journal Circulation, the anti-inflammatory properties of HDLs could be an even better biomarker for future cardiovascular events. Atherosclerosis is considered a chronic local inflammation that leads to plaques in the blood vessels and that, if left untreated, can cause cardiovascular disease, the most common cause of death in the world. The inflammation, while unnoticeable, can cause considerable damage to the blood vessels, so it is important to identify at-risk individuals as early as possible to curb progression of the disease.

Another way good cholesterol is good: combatting inflammation

American Heart Association Research Highlights: The ability of HDL particles (commonly known as “good” cholesterol) to reduce inflammation in the cells that line blood vessels may help predict who is more likely to develop a heart attack or other serious heart-related event. Gauging the anti-inflammatory capacity of HDL cholesterol may one day improve standard heart disease risk assessment. The results may encourage greater attention to the function of HDL particles in addition to quantity of cholesterol within HDL in determining how to assess and reduce heart disease risk. DALLAS, April 12, 2021 Testing how well “good” cholesterol particles reduce inflammation may help predict who is at heightened risk to develop cardiovascular disease caused by narrowed arteries, according to research published today in the American Heart Association’s flagship journal

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