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When Will PA Reach Herd Immunity? Experts Weigh In
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Will Cruises Be Back in 2021 and Will Vaccines Be Mandatory?
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Two Popular Screening Tests for Gestational Diabetes Equivalent
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Researchers discover new molecular target that could treat idiopathic pulmonary fibrosis
Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF). The study, which will be published March 10 in the
Journal of Experimental Medicine (
JEM), suggests that targeting a protein called MDM4 could prevent respiratory failure by initiating a genetic program that removes scar tissue from the lungs.
IPF is characterized by the accumulation of scar tissue that stiffens the lungs and makes it difficult for patients to breathe and get sufficient oxygen into their blood. Though the causes of IPF remain unclear, age is a significant risk factor: the disease is estimated to affect 1 in 200 US adults over the age of 70.