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Hyacinth Empinado/STAT
With Covid-19 vaccines, the world hopes to beat back the virus that causes the disease. But some scientists are increasingly concerned that, because of a quirk of our own biology, future iterations of the vaccines might not always be quite as effective as they are today.
The concerns stem from a phenomenon that is known as imprinting, sometimes called original antigenic sin, which is believed to affect how we respond to some pathogens.
In short, when your body is introduced to a particular threat for the first time either through infection or a vaccine that encounter sets your immune system’s definition of that virus and what immune weapons it needs to detect and protect against it in the future.