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Under normal, healthy circulatory conditions, the von Willebrand Factor (vWF) keeps to itself. The large and mysterious glycoprotein moves through the blood, balled up tightly, its reaction sites unexposed. But when significant bleeding occurs, it springs into action, initiating the clotting process.
When it works properly, vWF helps stop bleeding and saves lives. However, according to the Centers for Disease Control and Prevention (CDC), about 60,000 to 100,000 Americans die each year from thrombosis, a disorder characterized by too much clotting. Blood clots can trigger a stroke or heart attack.
According to X. Frank Zhang, associate professor in the Department of Bioengineering at Lehigh University, only one drug has been FDA-approved to target vWF and treat thrombosis, or excessive blood clotting disorders, Caplacizumab. It works by binding to vWF and blocking it from binding to platelets. However, no one has understood the specific mechanism behind how it accomplis
Harry Pettit, Senior Digital Technology and Science Reporter
Apr 28 2021, 10:40 ET
SEX in space is possible, though bonking astronauts will have to battle through a low sex drive and erectile dysfunction, experts claim.
Speaking to Russian outlet Sputnik News this week, space researchers discussed the challenges that couples might face on trips to alien worlds.
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Jennifer Lawrence and Chris Pratt smooch in 2016 s PassengersCredit: Alamy
Rompers will have to learn how to connect body parts in weightlessness, as well as fit in time for lovemaking around their busy work schedules.
The UK’s universities are institutionally racist, the Vice-Chancellor of UEA has admitted.
“There’s a lot of evidence that points towards universities perpetuating systemic racism,” Professor David Richardson – who also leads a national body looking into racism in universities – told the BBC.
“Historically, students who have experienced racial harassment, have not felt able to report it or felt safe to report it,” he added.
The comments were made as Richardson spoke to the BBC as part of a documentary – Is Uni Racist? – investigating racism on campus.
Richardson leads Universities UK’s advisory group on racial harassment. In November, the group told universities across the country to do better at tackling racism.
What is the Peer-to-Peer Simulation Hypothesis?
The idea that we may be living inside of a computer simulation is not new. It was famously depicted in the 1998 film The Matrix and argued to be probable by philosopher Nick Bostrom. However, most forms of the simulation hypothesis (including Bostrom s) are purely speculative. They do not explain or make predictions about the world we perceive.
Is based on serious scientific and philosophical hypothesies.
Explains features of the physical world (including quantum world) that no other theory explains.
Makes predictions about our world, and so may be confirmed or falsified.
The P2P hypothesis holds that we are living in a peer-to-peer networked computer simulation. Some computer simulations have a dedicated centeral server (a single computer running the simulation that all other computers access). However, peer-to-peer networked simulations have no central server. The simulated reality is simply a vast netw
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