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Kidney biopsy analyses cause potentially transplantable organs to be discarded

Highlights When determining whether kidneys are suitable for transplantation in the United States, biopsy analyses don t provide useful information beyond standard donor and recipient characteristics. Many kidneys discarded based on biopsy findings would likely benefit U.S. patients who are waiting for a transplant. Washington, DC (December 15, 2020) New research indicates that analyses of kidney biopsies from deceased donors don t provide meaningful information beyond standard assessments of donor and recipient characteristics. In addition, the study revealed that relying on these analyses has prompted the discard of many potentially suitable organs for transplantation in the United States. The findings appear in an upcoming issue of

COVID-19 news from Annals of Internal Medicine

Accounting for recent population aging is critical for estimating non-COVID-19 excess deaths in the U.S. Estimates of excess mortality during the coronavirus disease 2019 (COVID-19) pandemic provide an important metric for quantifying deaths due to COVID-19 as well as those indirectly caused by COVID- 19. To evaluate the excess deaths in 2020 without consideration of changes to the underlying population structure can result in overestimated excess deaths. The growth of the U.S. population, particularly in older age groups, means a higher expected number of deaths in 2020 from all causes, even in the absence of COVID-19. Researchers from the National Cancer Institute used data from the CDC National Center for Health Statistics and the U.S. Census Bureau to estimate excess mortality in the period March through August 2020. By accounting for the recent aging of the population, they found the number of excess non-COVID-19 deaths was 44,600, which is 65 percent fewer than estimated

Garcia to head Department of Biochemistry and Molecular Biophysics – Washington University School of Medicine in St Louis

University of Pennsylvania Benjamin Garcia, PhD, has been named head of the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine in St. Louis. His appointment is scheduled to begin July 1. Benjamin A. Garcia, PhD, a noted leader in the field of biochemistry, especially for his work advancing mass spectrometry techniques, has been named head of the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine in St. Louis. Garcia, whose appointment tentatively is set to begin July 1, also will become the Raymond H. Wittcoff Distinguished Professor. The school’s Department of Biochemistry and Molecular Biophysics has an illustrious history as home to some of the nation’s most distinguished scientists, including scientific innovator Roy Vagelos, who headed the department then called the Department of Biological Chemistry from 1966-75 and went on to lead the development of cholesterol-lowering statin

What is Covid vaccine made of? Scientist behind Pfizer and Moderna vaccine technology explains OLD

What is Covid vaccine made of? Scientist behind Pfizer and Moderna vaccine technology explains OLD Justin Vallejo © Provided by The Independent With Covid-19 vaccines expected within weeks, the scientist behind experimental technology used by pharmaceutical companies Pfizer and Moderna explains what will be baked into the first batch off the production line. Dr Drew Weissman, a professor in the University of Pennsylvania s Perelman School of Medicine, pioneered the vaccine formula called Messenger RNA (mRNA) and collaborated with Pfizer and BioNTech on their version of the vaccine. He told The Independent that the vaccine, unlike any that has been developed previously, contains a new technology that delivers genetic code - or directions - that instructs the body to create a copy of the Covid-19 virus protein, which prompts an immune response.

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