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Seven blood clot deaths after 18 1 million jabs, AstraZeneca vaccine safe: UK regulator

Covid: further rare blood clot cases found in Oxford/AstraZeneca recipients

The EMA says it has looked into 14 deaths reported by 22 March related to unusual blood clots in recipients of the jab, although not all of these were associated with CVST. Estimates of CVST in an unvaccinated population vary, but it is rare, with upper estimates of 15 to 16 cases per million people per year. At present, most of these rare clotting events appear to be occurring in women under the age of 65 – but quite why this is remains unclear. Some have said CVST is more common in this group in general, while others have noted that countries such as Germany were initially reluctant to approve the Oxford/AstraZeneca jab for older people, meaning most of the recipients were younger people, primarily healthcare workers and teachers – the majority of whom are women. This may also explain the apparent disparities between Germany and the UK, as the latter approved the jab for older people from the off.

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