A high rate of genetic mutations within a tumor, known as high tumor mutation burden (TMB), was only useful for predicting clinical responses to immune.
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Jason McLellan in his lab on January 18, 2021.
Credit: Matt Wright-Steel
On January 6, 2020, Jason McLellan and his wife, Jinelle, were in Park City, Utah, for their family’s first-ever snowboarding vacation. It was a chance for the couple and their two young kids to relax after the holidays and before the spring semester kicked off at UT, when McLellan would begin his second year as an associate professor in molecular biosciences.
McLellan’s new snowboarding boots were pinching him, so he stopped at a shop to get them heat-molded to his feet. While he waited, McLellan saw Barney Graham’s name flash across his phone. The pair had first met in 2008 at the National Institutes of Health (NIH), where Graham is deputy director of the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center, and McLellan was conducting his postdoctoral research in structure-based vaccine design after receiving his PhD from Johns Hopkins.