/PRNewswire/ INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from.
Trial for
Efficacy), evaluating INO-4800, its DNA vaccine candidate for COVID-19. Preliminary results show in a larger population that INO-4800 was generally safe, well-tolerated and immunogenic in all studied age groups.
Findings from the Phase 2 Clinical Trial:
The Phase 2 segment of the trial enrolled approximately 400 participants, 18 years of age or older, at 16 U.S. sites.
Participants received either INO-4800 (1.0 mg or 2.0 mg dose) or placebo at 0 and 4 weeks (randomized 3:3:1:1). Each dose was administered by intradermal injection followed by electroporation using INOVIO s CELLECTRA
®, its proprietary smart device.
Safety endpoints included systemic and local administration site reactions through 8 weeks post-dose one (or 4 weeks post-dose 2). Immunology endpoints included antigen-specific binding antibody titers, neutralization titers, and antigen-specific interferon-gamma (IFN-γ) cellular immune responses after two doses of the vaccine.
The PPB program aims to address PPE limitations.
May 7th, 2021
DARPA
Chemical and biological (CB) threats have become increasingly ubiquitous and diverse, presenting significant risks to warfighters in theater and stability operators during pandemic outbreaks. State-of-the-art personal protective equipment (PPE) can be bulky, heavy, and cumbersome, often severely limiting user mobility and performance. The Personalized Protective Biosystem (PPB) program aims to develop technology that reduces the need for burdensome protective equipment while increasing individual protection against CB threats.
DARPA recently awarded contracts to the following performers, FLIR Systems, Leidos, and Charles River Analytics, to develop lightweight materials and adaptable, tissue-protective countermeasures to provide on-demand, broad spectrum, and rapid long-term protection. Performers will seek to leverage molecular technologies and commensal organisms to unburden protective equipment demands from t
Rigel Reports First Quarter 2021 Financial Results and Provides Business Update
- Reported positive topline results of fostamatinib in Phase 2 clinical trial in hospitalized patients with COVID-19
- Net product sales of $12.4 million and total revenues of $81.0 million
- Received upfront cash payment of $125 million from Eli Lilly for the exclusive license agreement for Rigel s RIP1 inhibitor program
- Conference call and webcast today at 4:30PM Eastern Time
News provided by
Share this article
Share this article
SOUTH SAN FRANCISCO, Calif., May 5, 2021 /PRNewswire/ Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today reported financial results for the first quarter ended March 31, 2021, including sales of TAVALISSE
What You Should Know:
– Today, PhysIQ Inc. announced its partnership with Johns Hopkins University, Duke University and The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), to support a clinical trial to evaluate products for early treatment and post-exposure treatment of COVID-19. The 18-month study will assess disease progression and provide early indication of infection. This DOD-funded initiative will assess the role of continuous biosensor data and artificial intelligence in addressing the COVID-19 pandemic.
– Confirmed COVID-19 positive individuals and patients at high risk of exposure will wear a clinical-grade biosensor that continuously streams data to PhysIQ’s pinpointIQTM platform where advanced FDA-cleared analytics will process the raw biosensor data. In addition to capturing continuous physiological data, patients will also use physIQ’s mobile app to submit pulse oximeter measurements and report symptoms.