E-Mail
COLUMBUS, Ohio - An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.
In a new study, scientists identified a molecule that is produced by immune cells during mechanical ventilation to try to decrease inflammation, but isn t able to completely prevent ventilator-induced injury to the lungs.
The team is working on exploiting that natural process in pursuit of a therapy that could lower the chances for lung damage in patients on ventilators. Delivering high levels of the helpful molecule with a nanoparticle was effective at fending off ventilator-related lung damage in mice on mechanical ventilation.
Scientists identify target to treat COVID pneumonia and reduce severity
Clinical trials with new experimental drug to begin early in 2021
Goal is to develop treatments that make COVID-19 no worse than a common cold
First comparison between immune mechanisms driving COVID-19 pneumonia with other pneumonias
CHICAGO - Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung over the course of hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body s immune system within the first few days of the illness.
But in a study published in
Credit: Linkoping University
When an accident occurs, the reactions of bystanders are important. Researchers have studied whether laypeople realise the severity of the situation when someone in their proximity begins to bleed, and whether they can estimate how much the person is bleeding. The results show a discrepancy related to the victim s gender: for a woman losing blood, both blood loss and life-threatening injuries were underestimated. The study has been published in the scientific journal
PLoS One.
Researchers from Linköping University and Old Dominion University in the United States wanted to study the ability of laypeople to visually assess blood loss, and what influences them when judging the severity of an injury.
Loading video.
VIDEO: The MCM ward (450 m2 or 15m X 30m) accommodates four negative pressure bed rooms, nurse station, locker room, and treatment room. view more
Credit: KAIST
A team from KAIST has developed a low-cost and ready-for-rapid-production negative pressure room called a Mobile Clinic Module (MCM). The MCM is expandable, moveable, and easy to store through a combination of negative pressure frames, air tents, and multi-function panels.
The MCM expects to quickly meet the high demand for negative pressure beds in the nation and eventually many other countries where the third wave of COVID-19 is raging. The module is now ready to be rolled out after a three-week test period at the Korea Cancer Center Hospital.