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"Evolution of RND efflux pumps in the development of a successful patho" by Varsha Naidu, Amelia Bartczak et al.

Aims: This study examined the origins and evolution of the AdeABC, AdeFGH and AdeIJK efflux pumps in the Acinetobacter genus, including human and animal pathogens and species from non-clinical environments. Methods: Comparative genome analyses were performed using the reference sequences for 70 Acinetobacter species to identify putative orthologs of AdeABC, AdeFGH and AdeIJK and their regulators. Sequence similarities and the genomic locations of coding sequences were correlated with phylogeny t...
Membrane Transport Ultidrug Efflux
Source: uow.edu.au

Screening patients for hidden reservoirs of bacteria could supplement infection-control efforts in hospitals

Hospitals have strict hygiene and sanitation protocols to protect patients from bacteria that rarely sicken healthy people but can be deadly for vulnerable patients already hospitalized with serious illnesses.
Mario Feldman Helenl Stoever Scottj Hultgren Jenniee Hazen Emily Henderson Researchers At Washington University School Of Medicine

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Enormous rise in Acinetobacter bloodstream infection cases in initial two years of COVID-19

In a new study, researchers investigated Acinetobacter species bloodstream infection (BSI) case counts from a subset of laboratory data continuously reported during the initial two years of SARS-CoV-2 infections, i.e., from 2020 to 2021.
United Kingdom Czech Republic Kateryna Kon Shutterstock European Union Coronavirus Disease Covid 19 Covid 19

Antibodies can prevent surface proteins of bacteria from entering host cells

Using bacteria of the Bartonella henselae species, researchers from Goethe University, Frankfurt University Hospital, the Paul Ehrlich Federal Institute for Vaccines and Biomedicines in Langen, and the University of Oslo demonstrated for the first time that antibodies can prevent certain surface proteins of bacterial pathogens from entering host cells.
Volkhard Kempf Emily Henderson Frankfurt University Hospital Bacterial Adhesin Network Training German Research Foundation Goethe University

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