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Myeloid immune cells in the blood tied to severe COVID-19

 E-Mail Credit: Ulf Sirborn Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease. Researchers at Karolinska Institutet in Sweden have now been able to show that patients with severe COVID-19 have significantly elevated levels of a certain type of immune cells in their blood, called myeloid-derived suppressor cells. The study published in the Journal of Clinical Investigation may bring an increased understanding of how early immune resp...
United States Meng Yu Holden Maecker Inga Szurgot Jorgen Salde Sindhu Vangeti

New study on the role of monocytes in sarcoidosis

 E-Mail The cause of the inflammatory lung disease sarcoidosis is unknown. In a new study, researchers at Karolinska Institutet in Sweden have investigated whether a type of immune cell called a monocyte could be a key player in sarcoidosis pathogenesis and explain why some patients develop more severe and chronic disease than others. The study, which is published in The European Respiratory Journal, opens new possibilities for future diagnostic and therapeutic methods. Sarcoidosis is an inf...
Karolinska Institutet Matteo Bottai Johan Grunewald Anders Blomberg King Gustaf Jamshid Pourazar

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