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Biotherapeutic regulatory filingsrequire detailed characterization of degradation pathways including aggregation. Learn how three orthogonal light scattering techniques complement each other to analyze and quantify soluble and sub-micron insoluble aggregates. This poster describes the capabilities of SEC-MALS, FFF-MALS and CG-MALS and how they work together to provide a comprehensive picture of irreversible and reversible aggregates.

Oncology drug discovery capabilities Geaneth Martins Zeni, laboratório central prefeitura de vitória ES Jason Wong, Anresco Laboratories Fnu Adnan, University of Swat Tanya Singh, Cardiff University Help over Be the first to review brand new products help shape new technologies June 13 May 2021 In this application note, explore how Charles River can support every phase of oncology drug discovery ...

Fast and automated TSA-based multiplexed immunofluorescence Geaneth Martins Zeni, laboratório central prefeitura de vitória ES Jason Wong, Anresco Laboratories Fnu Adnan, University of Swat Tanya Singh, Cardiff University Help over Be the first to review brand new products help shape new technologies June 13 May 2021 TSA-based multiplexing is a precise tool in immunostaining to unravel the comple...

The Ionic system produces more higher quality nucleic acid due to less fragmentation and no risk of contamination from wash buffers or beads. When higher quality material is input into downstream analysis, superior results can be obtained; providing more biological insight for researchers or more robust and reliable results for clinicians.

Simultaneous extraction and purification of both RNA and DNA from FFPE tissue samples is critical to enable multiple downstream analyses from rare or limited samples. To avoid yield loss, most technologies use a serial isolation approach where DNA and RNA are separated after lysis by filtration or precipitation before entering separate purification workflows. This results in twice the number of purification steps per sample.  With simultaneous extraction and

The Ionic FFPE Complete Purification Kit is used with the Ionic system to enable the automated purification of DNA and RNA, including microRNA from FFPE tissue samples. The kit provides a protocol, Ionic ® Fluidic Chips and reagents to enable the Ionic system to automate DNA and RNA purification using an innovative isotachophoresis technology. Samples are prepared for purification on the Ionic system using a simple lysis procedure that can be automated u

Bio-Plex Pro SARS-CoV-2 multiplex serology assays Chamila Rupasinghe, Progressive Diagnostics LLC Jean-François RAMEAU, Sanofi Lynn Cunningham, Adena Health System Donna James, Piedmont Interventional Pain Care, PA Sudhir Sharma, New York University Abu Dhabi Sunil Kumar Gahlaut, USV PRIVATE LTD Help over Be the first to review brand new products hel...

16 April 2021 Download this poster to discover the latest solution in the  Artel MVS product line that has been specifically engineered to reduce cost and time requirements in addition to generating the most accurate and reliable results for assays that contain master mix.    Download 10,000+

1 April 2021 Download this application note to learn more about flow cytometry panel design from this quick reference guide. Download 10,000+

31 March 2021 The liver is one of the organs most susceptible to drug toxicity and drug induced liver injury (DILI). DILI is a major cause of drug attrition, with more than 750 FDA approved drugs known to have a degree of DILI risk. There are a number of strategies to de-risk DILI in drug discovery and, in recent years, focus has turned to human in vitro 3D liver models to better predict DILI in early and pre-clinical development. These models culture primary human liver cells, often in co...