To ensure the quality of LNP-based drugs, comprehensive characterization of these sophisticated molecules is paramount. Explore how to achieve high-quality, robust assessment of the integrity and size of mRNA molecules encapsulated in LNPs.
In this infographic, GenScript presents its solutions to support gene and cell therapy research and development. GenScript presents solutions for target selection and validation, CRISPR editing and payload optimization, and transgene delivery optimization. Plus, GenScript explores solutions for extensive testing in animal models for feasibility, efficacy and safety, and cGMP manufacturing, documentation, and support to accelerate IND filing.
In recent years there has been a shift to analyzing smaller sample quantities, driven by the interest in profiling the proteome of individual cells. This increased focus on LC-MS analysis of limited sample amounts (e.g., single-cells) requires the highest possible sensitivity. At the same time, throughput and chromatographic performance must be preserved to generate sufficiently high-quality data from large data sets to draw meaningful conclusions. Traditional proteomics approaches read out the
The need for high-throughput sample acquisition and automation in flow cytometry creates demand for new methods for analytical standardization and for reducing sources of variability. When performed on the Attune CytPix Flow Cytometer, automated image analysis combined with conventional flow cytometry provides a robust quantitative method for standardizing flow cytometry data analysis. In this application note, Thermo Fisher Scientific demonstrates that automated image-assisted analysis enabl