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Quantifying NK-mediated cytolysis of glioblastoma in vitro with Maestro Z

Immunotherapies such as CAR T cells that have shown success in treating liquid tumors have had limited efficacy against solid tumors, including glioblastoma. Natural killer (NK) cells represent a promising approach for solid tumor treatment, and understanding mechanisms of NK-mediated cytotoxicity is important for cell therapy development. In this application note, Axion Biosystems quantifies the kinetics of both antibody-dependent cellular cytotoxicity (ADCC) and CAR NK-mediated cytolysis a

Axion-biosystems
Application-note
Maestro-z
Lioblastoma
Nk-cells
Part-cells
Axion-biosystems

Antibody-dependent cellular cytotoxicity of natural killer cells

Trastuzumab promotes natural killer cell activation through antibody-dependent cellular cytotoxicity (ADCC). Understanding ADCC can help researchers develop immunotherapies with better targeting and efficacy. In this application note, Axion Biosystems examines and quantifies ADCC-specific killing using the monoclonal antibody trastuzumab and peripheral blood natural killer cells on the Maestro z. The ADCC response between donors and across multiple effector to target cell ratios is compared.

Axion-biosystems
Application-note
Natural-killer
Ntibodies
Cytotoxicity
Axion-biosystems
Dcc
Rastuzumab
Maestro-z

Axion Biosystems launches new high-throughput live-cell imaging platform, Omni Pro 12

Axion Biosystems has announced the addition of the Omni Pro 12 to the Omni live-cell imaging product family. The new platform, which features integrated robotics and a multiplate design compatible with any standard incubator, offers enhanced flexibility and efficiency to scientists and drug developers conducting live-cell imaging experiments.

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Axion-biosystems
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Research-development
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Analysis-systems
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Mni
Axion-biosystems

Axion BioSystems Launches New High-Throughput Live-Cell Imaging Platform, Omni Pro 12

Axion BioSystems Launches New High-Throughput Live-Cell Imaging Platform, Omni Pro 12 - read this article along with other careers information, tips and advice on BioSpace

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Resume

IonQ Opens Manufacturing Facility: Week in Brief: 01/27/23 | Business | Jan 2023

PASQAL, a developer of neutral atom quantum computing, secured a €100 million ($109 million) equity series B round led by new investor Temasek, a

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Printed Electronics Global Market Report 2022

Major players in the printed electronics market are Molex, LLC, Agfa-Gevaert Group, Palo Alto Research Center Incorporated (PARC), DuPont de Nemours, Inc..

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Axion BioSystems introduces the Maestro TrayZ Platform

Axion BioSystems has announced the Maestro TrayZ, an innovative, live-cell analysis platform designed for high-throughput drug development and therapeutic discovery. The new system—featuring a slim multiplate tray design that allows for modular scalability and fits comfortably inside an incubator—joins Axion’s growing suite of next-generation Maestro products and offers a flexible, affordable option for noninvasive, label-free monitoring of live cells in real time.

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Ive-cell-analysis-platform
Rug-development

BioCircuit Technologies, Inc. Closes a $9 million Series Seed Round

BioCircuit Technologies, Inc. Closes a $9 million Series Seed Round
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Mike-masters
Tom-obrien
Michelle-jarrard
Venture-fund
Circuit-technologies
Masters-capital
Alsora-capital
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CAR T cell potency assessment with 3D cancer spheroid models

A real-time, label-free potency assay for immune-cell mediated killing of 30 cancer spheroids has been developed.

Axion-biosystems
Application-note
Tumor-microenvironment
Ar-t
Cancer-spheroids
Potency-assessment

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